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Accumulation of glial fibrillary acidic protein and histone H4 in brain storage bodies of Tibetan terriers with hereditary neuronal ceroid lipofuscinosis
(Springer Netherlands, 2007)
and histone H4 in storage bodies has not been previously reported for any of the NCLs. Tibetan terrier NCL may be the canine correlate of one of the human adult-onset NCLs for which the genetic bases and storage body compositions have not yet been determined....
Composition, vigor, and proteome of mature soybean seeds developed under high temperature
(Crop Society of America, 1999)
The effects of high temperature treatment on soybean [Glycine max (L.) Merr.] seed composition, vigor, and proteome were investigated using mature dry seeds harvested from plants grown in environment-controlled chambers. ...
Guest and ligand behavior in zinc-seamed pyrogallol[4]arene molecular capsules
(Wiley-VCH, 2007)
Not just an inside job: Encapsulated and confined in an octanuclear zinc-seamed pyrogallol[4]arene molecular capsule, a guest of choice can act as a reporter for electronic communication between the exterior and the interior of the capsule through...
Kinetics and mechanism of protein tyrosine phosphatase 1B inactivation by acrolein
(American Chemical Society, 2007)
Human cells are exposed to the electrophilic [alpha],[beta]-unsaturated aldehyde acrolein from a variety of sources. The reaction of acrolein with functionally critical protein thiol residues can yield important biological ...
Prostaglandins A1 and E1 influence gene expression in an established insect cell line (BCIRL-HzAM1 cells)
(Elsevier, 2007)
, we have no information on the mechanisms of PGs actions in insect cells. Here we report on the outcomes of experiments designed to test our hypothesis that PGs modulate gene expression in an insect cell line established from pupal ovarian tissue...
Proteomics of canine lymphoma identifies potential cancer-specific protein markers
(American Association for Cancer Research, 2007)
Purpose: Early diagnosis of cancer is crucial for the success of treatment of the disease, and there is a need for markers whose differential expression between disease and normal tissue could be used as a diagnostic tool. ...
Anti-chaperone [eszett]A3/A1102-117 peptide interacting sites in human aB-crystallin
(Molecular Vision, 2008)
Purpose: Our previous work identified 23 low molecular weight (<3.5 kDa) crystallin peptides in the urea-soluble fractions of normal young, normal aged, and aged cataract human lenses. We found that one of these crystallin ...
Proteomic identification of PKC-mediated expression of 20E-induced protein in Drosophila melanogaster
(ACS, 2007)
is affected by phosphorylation. Using a proteomic approach, we have shown that protein kinase C (PKC) activity is necessary for mediating 20E-induced expression of 14 specific proteins, including three previously reported 20E responsive proteins, and is also...
Ubiquitin C-terminal hydrolase-activity is involved in sperm acrosomal function and anti-polyspermy defense during porcine fertilization
(Society for the Study of Reproduction, 2007)
The 26S proteasome, which is a multi-subunit protease with specificity for substrate proteins that are postranslationally modified by ubiquitination, has been implicated in acrosomal function and sperm-zona pellucida (ZP) ...
Significance of interactions of low molecular weight crystallin fragments in lens aging and cataract formation
(The American Society for Biochemistry and Molecular Biology, 2008)
Analysis of aged and cataract lenses shows the presence of increased amounts of crystallin fragments in the high molecular weight aggregates of water-soluble and water-insoluble fractions. However, the significance of ...
System analysis of an Arabidopsis mutant altered in de novo fatty acid synthesis reveals diverse changes in seed composition and metabolism
(American Society of Plant Biologists, 2009)
Embryo-specific overexpression of biotin carboxyl carrier protein 2 (BCCP2) inhibited plastid acetyl-coenzyme A carboxylase (ACCase), resulting in altered oil, protein, and carbohydrate composition in mature Arabidopsis ...