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Synthesis, Characterization and Device Studies of Conjugated Foldamers
(University of Missouri--Kansas City, 2017)
Conjugated polymers have found a wide range of electronic applications in last few
decades due to their superior combination of optoelectronic, mechanical properties, and
solution processability. In the past few years, ...
Discovery of PSMA-Specific Peptide Ligands and Development of A Noncovalent Method to Attach Chemical Moieties to siRNA
(University of Missouri -- Kansas City, 2017)
The objective of this dissertation is to discover PSMA (Prostate Specific Membrane
Antigen)-specific peptide ligands using phage display and employ peptide nucleic acid as
a complementary linker to attach chemical ...
Metabolomic Analysis of Bacterial Cell Wall Intermediates Using LC-MS/MS: Peptidoglycan Pathway Response to Different Antibiotics
(University of Missouri--Kansas City, 2017)
The bacterial cell wall is made up of peptidoglycan (PG) and its synthesis is of
interest as a target for several antibiotics and for new inhibitor development. Peptidoglycan
biosynthesis is a complex process which ...
Conformational Behavior and Structural Parameters of Some Cyclic and Chain Molecules
(University of Missouri--Kansas City, 2017)
The physicochemical properties of a molecule derive from its molecular structure, and
that structure often involves the orientation of one part of the molecule about a particular
bond with respect to the rest of the ...
Recent Advances in Hetaryne Chemistry. Efforts Toward the Development of a Single Platform for the Generation of 4,5-, 5,6-, and 6,7-Indole Arynes
(University of Missouri--Kansas City, 2017)
In the beginning of 2007, indole arynes and their cycloaddition chemistry were discovered
by Buszek laboratories. Since then, indole arynes and their cycloaddition chemistry have
demonstrated their value in the ...
Metals hosts in the Pennsylvanian Hushpuckney and Stark Black Shales from Selected Areas in Kansas City
(University of Missouri--Kansas City, 2017)
The Hushpuckney Shale of the Swope Formation and the Stark Shale of the Dennis
Formation, two black shales in the Pennsylvanian Kansas City group, contain elevated
concentrations of transition and based metal elements, ...
Positron interactions with oriented polymers and with chiral quartz crystals
(University of Missouri--Kansas City, 2017)
Positron annihilation in various materials has been applied to characterize
microstructure for decades. In this work, PALS was used to study material nanostructure,
with a focus on the size and density of free volume ...
Long Term Ocular Drug Delivery with Novel Pentablock Copolymers; Part I: Composite Nanoformulation of Macromolecules For Back of the Eye Diseases, Part II: Dexamethasone Nanoparticle to Develop an In Vitro Model for Glaucoma
(University of Missouri -- Kansas City, 2017)
Pentablock (PB) copolymers have been successfully synthesized for long term delivery in
the treatment of posterior segment ocular diseases. PB copolymers are comprised of FDA
approved biodegradable polymer such as ...