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The Effect of Drugs of Abuse and HIV-1 GP120 on Autophagy in Astrocytes
(University of Missouri--Kansas City, 2016)
The life expectancy of individuals infected with HIV-1 has significantly improved since the introduction of highly active anti-retroviral therapy (HAART). However, this has led to an increase in the prevalence of HIV-associated ...
HIV-1 gp120 and Methamphetamine-mediated Induction of Proinflammatory Cytokines/chemokines and Oxidative Stress in Astrocytes: Implications in Neuroinflammation
(2014-04-02)
HIV associated neurocognitive disorder (HAND) remains a major concern for patients infected with HIV. The viral envelope protein, gp120 has been extensively studied and some of its neurotoxic effects are due to the increased expression of various...
The effect of HIV-1 Tat and methamphetamine on expression of cytokines/chemokines and synaptic genes: Implications in HIV neuroAIDS
(University of Missouri--Kansas City, 2017)
Human immunodeficiency virus-1 (HIV-1) enters the brain through blood brain barrier
(BBB) early after the infection and leads to various neurological complications including HIV
associated dementia (HAD). Introduction ...