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Identification of Novel Regulatory Genes in Acetaminophen Induced Hepatocyte Toxicity by a Genome-Wide CRISPR/Cas9 Screen
(University of Missouri -- Kansas City, 2018)
Acetaminophen (APAP) is a commonly used analgesic responsible for over 56,000
overdose-related emergency room visits annually. A long asymptomatic period and limited
treatment options result in a high rate of liver ...