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Characterization of peptides and phage that bind galectin-3 selected from bacteriophage display libraries: a study of the role of galectin-3 in metastasis-associated cancer cell adhesion
(University of Missouri--Columbia, 2005)
identified peptide antagonists of galectin-3 using combinatorial bacteriophage (phage) display technology. The peptides bound with high affinity to purified galectin-3 protein and to cell surface galectin-3. Experiments with a series of recombinant serially...