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Characterization of the genetic landscape of feline oral squamous cell carcinoma
(University of Missouri--Columbia, 2022)
Over 94 million domestic cats are susceptible to cancers and other common and rare diseases. While cancer treatment in cats increasingly mirrors that available in humans, treatment failures are more frequent. There are no ...
Generation of a reference genome to investigate population fitness and transitional cell carcinoma occurrence in the fishing cat (Prionailurus viverrinus)
(University of Missouri--Columbia, 2022)
Many species are vulnerable or on the verge of extinction as a result of increased habitat degradation and fragmentation. Conservation genetics has attempted to apply an understanding of species genetics to reduce the risk ...
Heritable, differential gene expression in pre-implantation embryos from rats with endometriosis and their daughters
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Endometriosis, which affects millions of women, is a condition where the uterine lining grows outside of the uterus and is associated with subfertility ...
Temporal effects of fescue toxicosis and heat stress on rat physiology and hepatic gene expression
(University of Missouri--Columbia, 2007)
Fescue toxicosis results from intake of toxins in fescue containing an endophytic fungus, Neotyphodium coenophialum. Time-related changes in rats associated with intake of an endophyte-infected fescue diet (E+) were evaluated under thermoneutral (TN...
New perspective on the role of conceptus estrogens in conceptus development, maternal recognition, and the establishment of pregnancy in pigs.
(University of Missouri--Columbia, 2018)
The proposed signal for maternal recognition of pregnancy in pigs is estrogen, produced by the elongating conceptus. To understand the role of estrogen in porcine conceptus elongation and pregnancy establishment, a loss ...
Investigating the role of a lncRNA (4833427F10Rik) in mouse placental development and function
(University of Missouri--Columbia, 2022)
differentially expressed between the embryonic and extraembryonic tissues of E7.5 mouse conceptus. Specifically, a candidate lncRNA 4833427F10Rik had expression specific to the placental lineages in conceptus during early development stage. Both RT...
An analysis of aspartic peptidases expressed by trophoblasts and placenta of even-toed ungulates
(University of Missouri--Columbia, 2008)
The Pregnancy Associated Glycoproteins (PAGs) represent a multigene family of trophoblast expressed proteins, found exclusively in the placenta of even-toed mammals such as ruminants (cattle, sheep), pig, etc. In ruminants, ...
Role of preovulatory estradiol in uterine and luteal function
(University of Missouri--Columbia, 2018)
In beef heifers, expression of estrus at fixed-time artificial insemination (FTAI) was associated with increased preovulatory circulating concentrations of estradiol (E2) and increased pregnancy rates compared to heifers that were not detected...
Conceptus interferon gamma is essential for pregnancy maintenance in the pig
(University of Missouri--Columbia, 2021)
Establishment and maintenance of pregnancy in the pig is a complex process that relies on adequate communication between the conceptus and maternal uterine endometrium. During the peri-implantation period, the conceptuses ...
Gene expression profiling of bovine ovarian follicular selection
(University of Missouri--Columbia, 2006)
Lack of, or abnormal, ovarian follicular development is a major factor associated with impaired fertility in mammals. However, development of new treatments is limited by our poor understanding of ovarian follicular ...
The value of in-breeding in the improvement of the domestic animals
(University of Missouri--Columbia, 1917)
In this paper I shall take the stand of a neutral, and all literature and available material of value upon the subject both for and against, will be studied with a view of determining our present knowledge of in-breeding ...
DNA methylation in the early porcine embryo
(University of Missouri--Columbia, 2007)
Reproductive technologies such as in vitro fertilization, intracytoplasmic sperm injection, parthenogenetic activation, and somatic cell nuclear transfer are powerful procedures in the production of animals for agriculture, ...
Reduced autophagy contributes to inefficient DNA damage repair in mouse oocytes
(University of Missouri--Columbia, 2022)
The DNA damage is a major problem that, in somatic cells, leads to mutagenesis and premature aging. However, this is not the case in fully differentiated germ cells. Why DNA damage repair (DDR) machinery is not robust in ...
Biology of uterine glands : impact on reproductive function
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Pregnancy loss is the most common complication of human gestation, and roughly one-half of conceptions result in pregnancy loss, most frequently in the ...
Biology of uterine glands : impact on reproductive function
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Pregnancy loss is the most common complication of human gestation, and roughly one-half of conceptions result in pregnancy loss, most frequently in the ...
Differential gene and protein expression in pig nuclear transfer extraembryonic membranes and blastocyst stage embryos
(University of Missouri--Columbia, 2010)
Nuclear transfer (cloning) is the process of transferring a donor cell nucleus into an enucleated oocyte. The oocyte and donor cell are subsequently fused and activated to allow for nuclear reprogramming and continued ...
Characterization of progesterone receptor (PGR) mRNA and protein isoforms in the endometrium of cyclic and pregnant pigs
(University of Missouri--Columbia, 2010)
Disappearance of the progesterone receptor (PGR) from the uterine luminal epithelium (LE) is essential for cyclicity and pregnancy in pigs. In humans, three PGR mRNA isoforms (PGR-A, PGR-B and PGR-C) arise from alternative ...
Regulation of fetal brain development in short versus long lived mice
(University of Missouri--Columbia, 2022)
How fetal brain development is regulated in mice with reduced life span is a primary objective of this research. Three studies were performed to investigate the fetal brain development in short and lived mice strains. The ...
Cotton seed and cotton-seed products as feeds for live stock
(University of Missouri--Columbia, 1916)
The purpose of this work was to get together the results of the different experiments with cotton seed and cotton seed products in order that comparisons might be made of the feeding values of the different products with ...