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Neoadjuvant treatment of Dermatofibrosarcoma Protuberans of pancreas with Imatinib: case report and systematic review of literature
(2014-08-06)
Abstract
Dermatofibrosarcoma Protuberans (DFSP) is a rare skin tumor, characterized by frequent local recurrence but is seldom metastatic. It is histologically characterized by storiform arrangement of spindle ...
Meeting report: 2nd workshop of the United States culture collection network (May 19-21, 2014, State College, PA, USA)
(2014-12-29)
This report summarizes the activities and outcomes of the second workshop of the US Culture Collection Network, formally an activity of the US National Science Foundation sponsored Research Coordination Network for a ...
Prehospital intravenous access and fluid resuscitation in severe sepsis: an observational cohort study
(2014-09-27)
Abstract
Introduction
Prompt treatment of severe sepsis in the Emergency Department reduces deaths, but the role of prehospital ...
TRIP-1 via AKT modulation drives lung fibroblast/myofibroblast trans-differentiation
(2014-02-15)
Abstract
Background
Myofibroblasts are the critical effector cells in the pathogenesis of pulmonary fibrosis which carries a high degree of morbidity and mortality. We have previously identified ...
Investment into the future of microbial resources: culture collection funding models and BRC business plans for biological resource centres
(2014-02-12)
Through their long history of public service, diverse microbial Biological Resource Centres (mBRCs) have made myriad contributions to society and science. They have enabled the maintenance of specimens isolated before ...
Separating signal from noise: the challenge of identifying useful biomarkers in sepsis
(2014-03-17)
Abstract
Sepsis diagnosis remains based largely on clinical presentation despite significant advances in the understanding of underlying pathophysiology and host-pathogen interactions. The systematic review article by ...
Factors associated with sterilization use among women leaving a U.S. jail: a mixed methods study
(2014-07-31)
Abstract
Background
Despite the high rates of reported sterilization use among women who have spent time in correctional facilities, little is known about the context in which women in this ...
Combined meta-analysis of systemic effects of allogeneic stem cell transplantation and systemic sclerosis
(2014-03-22)
Abstract
Background
Chronic graft-versus-host disease (cGVHD) is a major factor of morbidity and mortality for allogeneic stem cell transplantation (aSCT). The skin and internal organ involvement ...
Cardiac thromboxane A2 receptor activation does not directly induce cardiomyocyte hypertrophy but does cause cell death that is prevented with gentamicin and 2-APB
(2014-12-17)
Abstract
Background
We have previously shown that the thromboxane (TXA2) receptor agonist, U46619, can directly induce ventricular arrhythmias that were associated with increases in intracellular ...
Regional pulse wave velocities and their cardiovascular risk factors among healthy middle-aged men: a cross-sectional population-based study
(2014-01-13)
Abstract
Background
Both carotid-femoral (cf) pulse wave velocity (PWV) and brachial-ankle (ba) PWV employ arterial sites that are not consistent with the path of blood flow. Few previous ...
Visual gene-network analysis reveals the cancer gene co-expression in human endometrial cancer
(2014-04-23)
Abstract
Background
Endometrial cancers (ECs) are the most common form of gynecologic malignancy. Recent studies have reported that ECs reveal distinct markers for molecular pathogenesis, ...