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A better approach to preventing active TB?
(Family Physicians Inquiries Network, 2020)
A better approach to preventing active TB? Nine months of isoniazid prevents active TB in those with latent disease. But is there a shorter, less toxic option? PRACTICE CHANGER: Use 4 months of rifampin instead of 9 months ...
Solid pseudopapillary neoplasm of the pancreas : clinical-radiological-pathological characteristics of four pediatric cases
(Journal of Gastroenterology Pancreatology and Hepatobilary Disorders, 2020)
Solid Pseudopapillary Neoplasm (SPN) of the pancreas represents 1-3 % of all exocrine pancreatic tumors and is uncommon in children. We report four pediatric patients with SPN where each patient posed a unique diagnostic ...
Does vitamin D supplementation reduce asthma exacerbations?
(Family Physicians Inquiries Network, 2020)
Q: Does vitamin D supplementation reduce asthma exacerbations? Evidence-based answer: YES, to some extent it does, and primarily in patients with low vitamin D levels. Supplementation reduces asthma exacerbations requiring ...
Do prophylactic antipyretics reduce vaccination-associated symptoms in children?
(Family Physicians Inquiries Network, 2020)
Q: Do prophylactic antipyretics reduce vaccination-associated symptoms in children? Yes for acetaminophen, not so much for ibuprofen. Prophylactic acetaminophen reduces the odds of febrile reactions in the first 48 hours ...
How old is too old for statins?
(Family Physicians Inquiries Network, 2020)
How old is too old for statins? When to start, continue, or stop statins in those ages [greater than or equal to] 75 years has been a quandary. Here 's why 2 studies have to say. PRACTICE CHANGER: Do you start a statin in ...
Which medications work best for menorrhagia?
(Family Physicians Inquiries Network, 2020)
Q: Which medications work best for menorrhagia? Evidence-based answer: Four medications have been shown to reduce menstrual blood loss (MBL) significantly in placebo-controlled randomized controlled trials (RCTs): the ...
Ruling out PE in pregnancy
(Family Physicians Inquiries Network, 2020)
Can clinical probability and a high-sensitivity D-dimer test reliably and safely rule out pulmonary embolism during pregnancy? PRACTICE CHANGER: Use a clinical probability score to identify patients at low or intermediate ...
Does early introduction of peanuts to an infant's diet reduce the risk for peanut allergy?
(Family Physicians Inquiries Network, 2020)
Q: Does early introduction of peanuts to an infant's diet reduce the risk for peanut allergy? Evidence-based answer: Probably not, unless the child has severe eczema or egg allergy. In a general pediatric population, ...
What is the best treatment for wrist ganglion cysts?
(Family Physicians Inquiries Network, 2020)
Q: What is the best treatment for wrist ganglion cysts? Evidence-based answer: Open surgical excision of wrist ganglion cysts is associated with a lower recurrence rate than aspiration with or without corticosteroid injection ...
Does evidence support the use of supplements to aid in BP control?
(Family Physicians Inquiries Network, 2020)
Q: Does evidence support the use of supplements to aid in BP control? Evidence-based answer: Yes. A number of well-tolerated natural therapies have been shown to reduce systolic and diastolic blood pressure (BP). (See ...
Does XR injectable naltrexone prevent relapse as effectively as daily sublingual buprenorphine-naloxone?
(Family Physicians Inquiries Network, 2020)
Q: Does XR injectable naltrexone prevent relapse as effectively as daily sublingual buprenorphine-naloxone? Evidence-based answer: Yes. Monthly extended-release injectable naltrexone (XR-NTX) treats opioid use disorder as ...
Can drinking more water prevent urinary tract infections?
(Family Physicians Inquiries Network, 2020)
Can drinking more water prevent urinary tract infections? A high-quality randomized controlled trial says 'Yes'. PRACTICE CHANGER: Advise premenopausal women with recurrent urinary tract infections (UTIs) and low-volume ...
Q: Can family physicians accurately screen for AAA with point-of-care ultrasound?
(Family Physicians Inquiries Network, 7/8/2021)
Evidence-based answer: LIKELY YES. Point-of-care ultrasound (POCUS) screening for abdominal aortic aneurysm (AAA) by nonradiologist physicians is 98% sensitive and 99% specific, compared with imaging performed by radiologists ...
Narrative ephemera : documents in storytelling worlds
(2020)
PURPOSE: Some virtual, immersive stories are filled with documents that users must locate and interact with to experience a narrative. Exploring a new area of inquiry in the information science field, this study focuses ...
Do cinnamon supplements improve glycemic control in adults with T2DM?
(Family Physicians Inquiries Network, 2020)
Q: Do cinnamon supplements improve glycemic control in adults with T2DM? Evidence-based answer: the answer isn't clear. Cinnamon supplements for adults with type 2 diabetes haven't been shown to decrease hemoglobin A1C ...
Do Areas with More Primary Care Physicians have Lower Cardiovascular and Cancer Mortality?
(University of Missouri, Department of Medicine, Division of Hospital Medicine, 2020-01)
"There are an estimated 647 000 deaths in the United states from cardiovascular disease (CVD) each year and 606 000 from cancer in 2019 [2,3] . Primary, secondary and tertiary prevention are all independent factors in ...
A re-challenging case
(University of Missouri, Department of Medicine, Division of Hospital Medicine, 2020-01)
"Immune Checkpoint Inhibitors (ICI) are associated with multiple cardiotoxic effects. Balancing adverse effects with anti-tumor response poses a challenge to treating advanced cancers. The safety of re-starting ICI therapy ...
When to Think Zebras, Not Horses: A Case of Delayed Care in anti-NMDA Receptor Encephalitis
(University of Missouri, Department of Medicine, Division of Hospital Medicine, 2020-01)
"Anti-NMDA receptor encephalitis (NMDAr) presents a diagnostic challenge for clinicians due to its varying symptom presentation such as psychosis, abnormal behavior, and seizures. Given the presentation, and it only newly ...
A cloud on the horizon : a deadly complication of norepinephrine
(University of Missouri, Department of Medicine, Division of Hospital Medicine, 2020-01)
"Symmetrical peripheral gangrene is a life-threatening complication of norepinephrine which is associated with a high mortality rate (up to 40[percent]). It presents as bilateral distal limb gangrene without evidence of ...
Endoscopic Ultrasound for the Treatment of Gastric Variceal Bleeding in a Patient with Portal Cavernoma
(University of Missouri, Department of Medicine, Division of Hospital Medicine, 2020-07)
"A 30-year-old lady was admitted with two weeks of fever and right upper quadrant pain. She had a background of non-malignant, non-cirrhotic portal vein thrombosis (PVT) with cavernoma formation. There was no detected ...