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Development of an in vitro model of quail vasculogenesis [abstract]
(2010-02)
Blood supply to virtually all tissues depends on endothelial cells, which form the linings of blood vessels. Growth and formation of endothelial cells occurs in two ways. Vasculogenesis describes the initial proliferation ...
Applications of Energetic Materials and Copper Oxide Nanorods for Decontamination [abstract]
(2010-03)
We demonstrate the potential of nanoenergetic coatings and CuO nanorods to decontaminate surfaces infected with bacteria. The methods of decontamination include (i) fast combustion of an energetic paint applied on contaminated ...
Investigation and Optimization of Silorane-Based Polymer System [abstract]
(2010-03)
This research is a collaboration between Department of Oral Biology in the School of Dentistry at UMKC, Department of Chemistry in The College of Arts and Sciences at UMKC, Department of Chemistry at Missouri Science and ...
Translational Approach to Examine the Importance of Aerobic Fitness on Nonalcoholic Fatty Liver Disease [abstract]
(2010)
Low cardiorespiratory fitness, independent of physical activity levels, is the best predictor of early mortality and is linked to type 2 diabetes and CVD. In the absence of exercise training, it is believed that genetic ...
Derivation and characterization of LIF and FGF2 dependent Porcine Induced Pluripotent Stem Cells [abstract]
(2010-02)
Authentic embryonic stem cells (ESC) have probably never been derived from the inner cell mass (ICM) of pig, despite over 25 years of effort. Recently, several groups, including ours, have reported derivation of induced ...
The use of the Nintendo Wii for balance and cognition as a trement modality in occupational therapy in persons with multiple sclerosis for increased independence in activities of daily living [abstract]
(2010-03)
Objective: Examine the effectiveness of the Nintendo Wii on balance and cognition deficits to increase independence in activities of daily living for an individual with MS. Design: ABA single subject experimental design ...
Estrogen receptor and estrogen related receptor may corporatley regulate hypoxic gene expression [abstract]
(2010-03)
Tumor cells can undergo adaptation to the hypoxia environment created by rapid growth of tumor cells to persist growing. A main regulator of hypoxia induced gene expression is hypoxia-inducible factor (HIF), and HIF can ...
Targeting the guanylate cyclase c receptor with an agonist peptide from enterotoxegenic Y. Enterocolitica [abstract]
(2010-03)
Heat-stable enterotoxin peptides (ST's) are expressed by enterotoxigenic strains of bacteria in order to co-opt an endogenous ligand-receptor system that regulates fluid homeostasis within the gut. Bacteria such as E. coli, ...
An Electro-magnetic cell stimulator [abstract]
(2010-03)
A device to stimulate bone and muscle cell growth and possibly for treatment of bone and muscle injuries is presented. The device, called EStim, generates electric and magnetic pulses at programmable intervals. This device ...
Clinical Translation of Nanopharmaceuticals for Cancer Therapy [abstract]
(2010-02)
The most recent study involving 77,000 North American men has shown that regular prostate specific antigen (PSA) screening did not provide accurate diagnosis of prostate cancer and therefore did not save lives of cancer ...
Nanostructures for Diagnostics and Delivery [abstract]
(2010)
Nanostructures are increasingly being recognized for their novel applications in biological systems including nanomedicine— the application of nanoscale technologies for diagnosis, treatment and prevention of diseases. ...
Creation of 'Super Avastin': A New Nanomedicine Approach for the Treatment of PXE and AMD [abstract]
(2010-02)
Nanomedicine is an emerging medical area that utilizes nanoparticles for the detection and treatment of diseases. The ubiquitous place of gold in Nanomedicine stems from its chemical ability to serve in an unoxidized state ...
Acid-sensing ion channels as a novel target for drug addiction [abstract]
(2010-03)
Improving the treatment and prevention of drug addiction is an important goal for modern medicine. Ion channels have recently become very attractive targets in the search of new pharmacotherapies. Extracellular proton ...
Novel Nanostructured Organosilicate Nanoparticle Coatings for Chem-Bio Sensing [abstract]
(2010-03)
We present novel nanostructured organosilicate particulate based films and demonstrate that these materials have a great potential for chemical-biological sensor development. With unprecedented high surface areas (> 1400 ...
Plasticity of the temporomandibular joint in rabbits [abstract]
(2010-03)
The temporomandibular joint (TMJ) is one of the most complex joints in the mammalian body. Major changes in diet during weaning and corresponding responses of connective tissues of the feeding apparatus are incompletely ...
Potential role of Kallikrein 5 expression in metastatic dissemination of oral squamous cell carcinoma (OSCC) [abstract]
(2010-03)
OSCC is one of the top 10 causes of cancer deaths worldwide, with only a 50% 5-year survival rate, necessitating the discovery of novel biomarkers and therapeutic targets. Using cDNA microarray analyses, we identified ...
Prevalence of Vitamin D deficiency and insulin resistance among overweight children and adolescents : a data bse study [abstract]
(2010-03)
Introduction: Recent studies have suggested a link between low serum vitamin D levels and insulin resistance. Moreover, those who are overweight or obese tend to have a high prevalence of insufficient or fully deficient ...
Pupillary light reflex as new biomarker for autism [abstract]
(2010-03)
Autism spectrum disorders (ASDs) comprise an etiologically heterogeneous group of behaviorally diagnosed disorders defined by impairments in social skills, communication, and repetitive behaviors. Detection of biomarkers ...
Predictors of post discharge venous thromboembolism [abstract]
(2010-03)
Spencer et al (Arch Intern Med 2007) found that most venous thromboembolic (VTE) events were diagnosed in the 3 months following hospitalization. In this study, we sought to evaluate the predictors of post-discharge VTE. ...
Retrospective characterization of geriatric patients with fractures below the hip, and comparison of this patient population with geriatric hip fracture patients [abstract]
(2010-03)
Hip fractures are commonly responsible for increased morbidity and mortality in the geriatric population. Many studies have discussed the management and outcomes of geriatric hip fracture patients. However, little attention ...