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Comparative imaging of canine shoulder osteochondrosis lesions
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Over the last several years, papers have been published describing imaging techniques for the canine shoulder joint using both ultrasound and magnetic ...
Immunomodulators in feline asthma
(University of Missouri--Columbia, 2010)
Experimental asthma was induced in 10 cats using Bermuda grass allergen (BGA) and cats were randomly selected to receive either feG (1 mg/kg, PO) or saline for 2 weeks, followed by a 2 week washout period before receiving ...
Comprehensive characterization of canine meniscal pathology
(University of Missouri--Columbia, 2010)
Meniscal injury is one of the most common causes of pain and dysfunction in the human knee and canine stifle joint. In the canine patient, meniscal injury is usually secondary to cranial cruciate ligament rupture, and the ...
Immunomodulatory effects of opioids
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Opioids have been shown to modulate the immune system in animal models by affecting both the acquired and innate arms of the immune system. Many of ...
The antiendotoxin effects of polymyxin B in a feline model of endotoxemia
(University of Missouri--Columbia, 2010)
Introduction: Directed, effective therapies for feline sepsis are needed to reduce the high morbidity and mortality associated with this disease. Materials and Methods: We investigated the anti-endotoxin effects of PMB in ...
Development of a motor unit number estimation technique in normal dogs : a potential biomarker for canine degenerative myelopathy
(University of Missouri--Columbia, 2011)
Motor unit number estimation (MUNE) is an electrophysiologic technique for quantifying the lower motor neuron (LMN) system. MUNE has proven useful in evaluating and monitoring neurodegenerative diseases such as amyotrophic ...
Paradoxical dysuria among dogs with degenerative lumbosacral stenosis
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Degenerative lumbosacral stenosis (DLSS) is a multifactorial condition affecting predominantly large breed dogs. The combination of stenosis and ...
New strategies in canine corneal wound healing for the veterinary ophthalmic patient
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Canine corneal fibrosis is a significant clinical problem in veterinary ophthalmology. Corneal wound healing following injury or infection often results ...
Neurons projecting to the paraventricular nucleus of the hypothalamus are activated and contribute to cardiorespiratory responses to systemic acute hypoxia
(University of Missouri--Columbia, 2013)
Activation of peripheral and central chemoreceptors contributes to homeostatic responses that maintain optimal blood gas levels, including oxygen and carbon dioxide. Brainstem neurons in the nTS and CVLM integrate and ...
Molecular epidemiology of tick-borne Anaplasmataceae among client-owned dogs in Missouri
(University of Missouri--Columbia, 2012)
Several tick-borne agents of zoonotic ehrlichiosis or anaplasmosis are endemic to Missouri. Dogs are susceptible to the same infections and tick vectors, but their roles as models, sentinels or reservoirs are undefined. ...
Canine pharmacodynamic assays: applications in immune-mediated disease
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Immune-mediated diseases are commonly diagnosed in veterinary medicine and a high rate of mortality, expense and complications of immunosuppressive ...
The role of spontaneous bursts of muscle sympathetic nerve activity in mediating peripheral vascular responses and cardiovascular hemodynamics in resting man
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The ability for sympathetic nerve activity to dynamically evoke vasoconstriction is paramount for the regulation of blood flow and blood pressure. ...
Parenteral fish oil effects on plasma non-esterified fatty acids and systemic cytokine concentrations in dogs immediately following ovariohysterectomy
(University of Missouri--Columbia, 2012)
An extreme systemic inflammatory response may be observed in dogs that experience severe accidental trauma, such as being struck by a car. The inflammatory response may be so extreme that it complicates treatment and causes ...
The use of a lysostaphin fusion protein as a dry-cow treatment for chronic Staphylococcus aureua mastitis in dairy cattle
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This study evaluated the efficacy of a lysostaphin-fusion protein (Lyso-PTD) as a dry-cow therapy for the treatment of experimentally-induced chronic, ...
Vascular actions of insulin in cardiometabolic disease : effects of metformin, physical activity, and intrinsic aerobic fitness
(University of Missouri--Columbia, 2013)
Insulin has important vascular and metabolic actions. The vascular effects of insulin typically account for as much as 40-50% of insulin-stimulated glucose disposal. However, the vascular reactivity to insulin is impaired ...
Preclinical evaluation of 177Lu-BBR2 antagonist radiothearpy of prostate cancer
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Castration resistant prostate cancer (CRPC) is the second most common cause of cancer death in the United States. Current treatment protocols offer ...
Osteochondral allograft preservation in a serum-free chemically-defined media
(University of Missouri--Columbia, 2011)
Articular cartilage has a very limited capacity as compared to other biological tissues to repair and regenerate because of its avascular nature. Chronic degradation of articular cartilage may result in osteoarthritis, the ...
The role and mechanisms of hexokinase-2-mediated protection against cardiac cell death and disease
(University of Missouri--Columbia, 2013)
Numerous cancer studies demonstrate that transformed cells exhibit both increased glucose metabolism and an increased propensity to survive in the face of stressful stimuli. These studies overwhelmingly correlate with ...
Physiological responses of adipose tissue to different models of physical activity and inactivity
(University of Missouri--Columbia, 2013)
Childhood is a critical time of growth, and decisions made during this time lead to positive and negative health consequences, specifically pertaining to adiposity. There is convincing evidence that children who are ...
Analysis of coffin and shoulder joint lameness with an inertial sensor-based system : impact versus pushoff
(University of Missouri--Columbia, 2012)
Reason for performing the study: An inertial sensor-based system (Lameness Locator[copyright] [LL]) can help veterinarians detect mild lameness. It would be beneficial if this tool could also be used to distinguish lamenesses ...