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Proteomics of canine lymphoma identifies potential cancer-specific protein markers
(American Association for Cancer Research, 2007)
Purpose: Early diagnosis of cancer is crucial for the success of treatment of the disease, and there is a need for markers whose differential expression between disease and normal tissue could be used as a diagnostic tool. ...
Ubiquitin C-terminal hydrolase-activity is involved in sperm acrosomal function and anti-polyspermy defense during porcine fertilization
(Society for the Study of Reproduction, 2007)
The 26S proteasome, which is a multi-subunit protease with specificity for substrate proteins that are postranslationally modified by ubiquitination, has been implicated in acrosomal function and sperm-zona pellucida (ZP) ...
Kinetics and mechanism of protein tyrosine phosphatase 1B inactivation by acrolein
(American Chemical Society, 2007)
Human cells are exposed to the electrophilic [alpha],[beta]-unsaturated aldehyde acrolein from a variety of sources. The reaction of acrolein with functionally critical protein thiol residues can yield important biological ...
Development and assessment of scoring functions for protein identification using PMF data
(Wiley-VCH, 2007)
PMF is one of the major methods for protein identification using the MS technology. It is faster and cheaper than MS/MS. Although PMF does not differentiate trypsin-digested peptides of identical mass, which makes it less ...
Guest and ligand behavior in zinc-seamed pyrogallol[4]arene molecular capsules
(Wiley-VCH, 2007)
Not just an inside job: Encapsulated and confined in an octanuclear zinc-seamed pyrogallol[4]arene molecular capsule, a guest of choice can act as a reporter for electronic communication between the exterior and the interior ...
Proteomic identification of PKC-mediated expression of 20E-induced protein in Drosophila melanogaster
(ACS, 2007)
Ecdysone receptor (EcR) and its heterodimeric partner, ultraspiracle protein (USP), are nuclear receptors that mediate the action of the insect molting hormone 20-hydroxyecdysone (20E). There is evidence that the activity ...
Establishment of a protein reference map for soybean root hair cells
(American Society of Plant Biologists, 2008)
Root hairs are single tubular cells formed from the differentiation of epidermal cells on roots. They are involved in water and nutrient uptake and represent the infection site on leguminous roots by rhizobia, soil bacteria ...
System analysis of an Arabidopsis mutant altered in de novo fatty acid synthesis reveals diverse changes in seed composition and metabolism
(American Society of Plant Biologists, 2009)
Embryo-specific overexpression of biotin carboxyl carrier protein 2 (BCCP2) inhibited plastid acetyl-coenzyme A carboxylase (ACCase), resulting in altered oil, protein, and carbohydrate composition in mature Arabidopsis ...
Peroxiredoxin 2 and peroxidase enzymatic activity of mammalian spermatozoa
(Society for the Study of Reproduction, 2009)
Peroxiredoxin 2 (PRDX2) is a highly efficient redox protein that neutralizes hydrogen peroxide resulting in protection of cells from oxidative damage and regulation of peroxide-mediated signal transduction events. The ...
Prostaglandins A1 and E1 influence gene expression in an established insect cell line (BCIRL-HzAM1 cells)
(Elsevier, 2007)
Prostaglandins (PGs) and other eicosanoids exert important physiological actions in insects and other invertebrates, including influencing ion transport and mediating cellular immune defense functions. Although these actions ...
Anti-chaperone [eszett]A3/A1102-117 peptide interacting sites in human aB-crystallin
(Molecular Vision, 2008)
Purpose: Our previous work identified 23 low molecular weight (<3.5 kDa) crystallin peptides in the urea-soluble fractions of normal young, normal aged, and aged cataract human lenses. We found that one of these crystallin ...
Maximal efficiency of coupling between ATP hydrolysis and translocation of polypeptides mediated by secB requires two protomers of secA
(American Society for Microbiology, 2008)
SecA is the ATPase that provides energy for translocation of precursor polypeptides through the SecYEG translocon in Escherichia coli during protein export. We have previously shown that when SecA receives the precursor ...
Cell wall proteome in the maize primary root elongation zone. II. Region-specific changes in water soluble and lightly ionically bound proteins under water deficit
(American Society of Plant Biologists, 2007)
Previous work on the adaptation of maize (Zea mays) primary roots to water deficit showed that cell elongation is maintained preferentially toward the apex, and that this response involves modification of cell wall extension ...
Significance of interactions of low molecular weight crystallin fragments in lens aging and cataract formation
(The American Society for Biochemistry and Molecular Biology, 2008)
Analysis of aged and cataract lenses shows the presence of increased amounts of crystallin fragments in the high molecular weight aggregates of water-soluble and water-insoluble fractions. However, the significance of ...
Accumulation of glial fibrillary acidic protein and histone H4 in brain storage bodies of Tibetan terriers with hereditary neuronal ceroid lipofuscinosis
(Springer Netherlands, 2007)
The neuronal ceroid lipofuscinoses (NCLs) are inherited neurodegenerative diseases characterized by massive accumulation of autofluorescent storage bodies in neurons and other cells. A late-onset form of NCL occurs in ...
Effect of a single AGE modification on the structure and chaperone activity of human alphaB-Crystallin
(American Chemical Society, 2007)
During aging, human lens proteins undergo several post-translational modifications, one of which is glycation. This process leads to the formation of advanced glycation end products (AGEs) which accumulate with time possibly ...
Composition, vigor, and proteome of mature soybean seeds developed under high temperature
(Crop Society of America, 1999)
The effects of high temperature treatment on soybean [Glycine max (L.) Merr.] seed composition, vigor, and proteome were investigated using mature dry seeds harvested from plants grown in environment-controlled chambers. ...