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Gene therapy in spinal muscular atrophy : RNA-based strategies to modulate the pre-mRNA splicing of survival motor neuron
(University of Missouri--Columbia, 2008)
Gene expression is the required process in eukaryotes in which DNA is transcribed into pre-mRNA, spliced to produce "mature" mRNA and translated into proteins. Inaccuracies in splicing events are receiving more attention ...
Metamorphism of the Wales Group and Moira Group on Prince of Wales and Dall Islands, southeastern Alaska
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This study examines the metamorphic history of the Proterozoic to Early Ordovician Wales Group and the newly-named Ordovician to Silurian Moira Group ...
Gene expression profiling of bovine ovarian follicular selection
(University of Missouri--Columbia, 2006)
Lack of, or abnormal, ovarian follicular development is a major factor associated with impaired fertility in mammals. However, development of new treatments is limited by our poor understanding of ovarian follicular ...
Analysis and modeling of direct selective laser sintering of two-component metal powders
(University of Missouri--Columbia, 2005)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Direct Selective Laser Sintering (SLS) is an emerging technology of Solid Freeform Fabrication (SFF) that 3-D parts are built from the metal-based ...
Putting physics first
(MU Alumni Association, University of Missouri, 2014)
Meera Chandrasekhar, an MU faculty member, wins a national award in part for improving high school science education....
Examination of metabolic and regulatory networks of desulfovibrio species
(University of Missouri--Columbia, 2004)
The sulfate-reducing bacteria are a morphologically diverse group of organisms characterized by the ability to couple the enzymatic reduction of sulfate to energy production and growth. This metabolic activity has profound ...
Who drives defense policy : elites or public interest?
(University of Missouri--Columbia, 2011)
With a massive budget deficit and an ever-increasing national debt, while Congress and the President almost shut down the federal government over funding for Planned Parenthood in 2011, defense spending seems to be nearly ...
Molecular cloning and characterization of regulatory enzymes in threonine biosynthetic pathway from soybean
(University of Missouri--Columbia, 2007)
Soybeans (Glycine max [L.] Merr.) are a good source of protein and oil. Despite being a very good source of protein, soybeans nutritional value is limited by low proportion of sulfur amino acids methionine and cysteine ...
Fluorescence spectroscopy and parallel factor analysis of waters from municipal waste sources
(University of Missouri--Columbia, 2007)
location. Parallel Factor Analysis (PARAFAC) has recently been used to effectively model EEM data sets. This thesis continues the study of the EEM/PARAFAC technique by applying it to waters of municipal waste sources. Bi-weekly samples were collected over a...
Statistical analysis of multivariate interval-censored failure time data
(University of Missouri--Columbia, 2007)
A voluminous literature on right-censored failure time data has been developed in the past 30 years. Due to advances in biomedical research, interval censoring has become increasingly common in medical follow-up studies. ...
Associations between cumulative genetic influence for risk-taking and hazardous alcohol use in two independent samples
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] A propensity for risk-taking may be associated with hazardous alcohol-related behaviors especially in men. Prior research indicating substantial ...
Calculated Height Tendencies in Two Southern Hemisphere Blocking and Cyclone Events: The Contribution of Diabatic Heating to Block Intensification
(American Meteorological Society, 2008-09)
The Zwack-Okossi vorticity tendency equation was used to calculate 500-hPa height tendencies in two intensifying Southern Hemisphere blocking events. The National Centers for Environmental Prediction-
National Center for ...
The effects of axotomy on the biophysical properties of reticulospinal neurons in larval lamprey
(University of Missouri--Columbia, 2006)
Following severe spinal cord injury (SCI), in adult higher vertebrates there is little or no axonal regeneration, and animals remain paralyzed below the lesion. In contrast, lower vertebrates such as the lamprey, following ...
Prospective radiolabled bombesin conjugates for prostate cancer imaging and therapeutic agents
(University of Missouri--Columbia, 2009)
-99m ([superscript 99][superscript-m]Tc), Copper-64 ([superscript 64 ]Cu) or Bismuth-213 ([superscript 213]Bi)....
From access to equity : student and instructor perspectives of ITV instruction
(University of Missouri--Columbia, 2019)
This mixed-methods grounded theory study examined student and faculty perceptions of engagement in Interactive Television (ITV) courses. The quantitative data included a Qualtrics survey comprised of both quantitative and ...
Effects of instructor-led feedback conferences on the level of reflective thought among senior-level students enrolled in a teaching methods course in agricultural education
(University of Missouri--Columbia, 2010)
The purpose of this experimental study was to describe the reflective thinking level of students both overall and by characteristics as well as to compare the effect of reflective feedback conference on students' reflective ...
Development of tailored preform processing technology for net-shape manufacturing of large monolithic structures
(University of Missouri--Columbia, 2007)
The aim of the present research effort involves exploration of a new processing approach, "Tailored Preform Processing (TPP)" technology for net-shape manufacturing of monolithic structures for the transportation industry. ...
Statistical analysis of clustered or multivariate interval-censored failure time data
(University of Missouri--Columbia, 2018)
of the presented methodology, an extensive simulation study is performed and suggests that the method works well in practical situations. Finally, the proposed approach is applied to a tumorigenicity experiment. Several directions for future research are discussed...
Understanding students' technology appropriation and learning perceptions in online learning environments
(University of Missouri--Columbia, 2005)
Distance education has the unique characteristic of using technologies as the primary means of delivery of instruction and interaction. The present study contributes to research dedicated to explaining or predicting phenomena ...