The work-up for secondary infertility--the inability to conceive after 1 year of regular unprotected intercourse for a couple who have previously had a child--should include a history and physical exam for both patients, ...

Ketoconazole (Nizoral) shampoo appears to be a safe and efficacious treatment for infants with cradle cap (strength of recommendation [SOR]: C, consensus, usual practice, opinion, disease-oriented evidence, and case series). ...

Punch biopsy excision appears to be superior to traditional wide elliptical excision for the treatment of sebaceous cysts when intervention is necessary (strength of recommendation [SOR]: B, based on 1 small randomized ...

The GAD-7 has the best evidence and utility in the primary care setting for generalized anxiety disorder (strength of recommendation [SOR]: A), while the proprietary Quick PsychoDiagnostics Panel (QPD) has the best operating ...

One of the most integral art forms central to musical expression is the visual and aural art of luthiery—a term which refers to the intricate craft, repair and restoration of stringed instruments. In May 2007, the Missouri ...

In the spring of 2006, however, while a graduate intern at the Missouri Folk Arts Program, I was able to observe firsthand an artist as he created art in what may seem the most unlikely of settings—a basement in urban St. ...

Excision or ablation of the transformation zone are equally effective for treating an initial diagnosis of cervical intraepithelial neoplasia (CIN) grades 2 or 3 in women with a satisfactory colposcopy and no suggestion ...

In African Americans with hypertension, therapy is best initiated with the low-sodium Dietary Approaches to Stop Hypertension (DASH) diet and a thiazide-type diuretic (strength of recommendation [SOR]: A, based on randomized ...

Routine vaccination with the meningococcal conjugate vaccine MCV4 (Menactra) is indicated for all US adolescents entering high school and for college freshmen living in dormitories (strength of recommendation [SOR]: B, ...

Depot medroxyprogesterone acetate (DMPA; Depo-Provera) and the combination contraceptive vaginal ring (NuvaRing) are most effective for obese women because they don't appear to be affected by body weight (strength of ...

Patients in intensive care unit (ICE) settings who are receiving prolonged mechanical ventilation (for >48 hours) or who have a coagulopathy or multiple organ dysfunction (especially renal failure) should receive stress ...

There is no single approach to glycemic control that is better than another for reducing neonatal mortality and morbidity. Glycemic control--regardless of whether it involves diet, glyburide, or insulin--leads to fewer ...

Although antibiotics are the best initial treatment, surgical intervention is warranted when a child has: visual impairment, complete ophthalmoplegia, or well-defined abscess on presentation, or no clearly apparent clinical ...

Obtain a urine culture in all men with suspected urinary tract infection (UTI), to reliably diagnose an infection (strength of recommendation [SOR]: C). For further evaluation, ultrasonography with abdominal radiography ...

A combination of beta-lactam and amino-glycoside antibiotics are the recommended empiric agents for the treatment of acute chorioamnionitis, given that no head-to-head trials exist (strength of recommendation [SOR]: C, ...

Prostaglandins (PGs) and other eicosanoids exert important physiological actions in insects and other invertebrates, including influencing ion transport and mediating cellular immune defense functions. Although these actions ...

This manuscript describes the IPI data collection categories, the use of those categories to support school-wide instructional change, and data findings from schools of various types that have used the IPI.

Patients with a prior hip fracture have 2.5 times the risk of a new fracture compared to age-matched persons without a previous hip fracture. For patients with a recent hip fracture, intravenous zoledronic acid annually ...

Previous work on the adaptation of maize (Zea mays) primary roots to water deficit showed that cell elongation is maintained preferentially toward the apex, and that this response involves modification of cell wall extension ...

The neuronal ceroid lipofuscinoses (NCLs) are inherited neurodegenerative diseases characterized by massive accumulation of autofluorescent storage bodies in neurons and other cells. A late-onset form of NCL occurs in ...