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Analyzing the effects of lactose on calcium absorption in premature infants using HR-ICP-Mass Spectrometry
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
With advances in neonatal care, premature infants are surviving at increasing rates. During the third trimester of pregnancy, the bone mineral content of infants rapidly increases. It is therefore becoming essential to ...
Expression and purification of AlgX in Pseudomonas aeruginosa
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Pseudomonas aeruginosa is a Gram-negative bacterium that is the leading cause of hospital acquired infections. While this bacteria is present in water and soil, this bacteria only severely affects severely ill patients, ...
Characterizing polymerization dynamics using fluorescent molecular rotors and magnetoelastic sensors
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
The dynamics of polymerization are critical in many medical applications; for instance, polymers used to fill aneurysms must be timed accurately. Two distinct methods were examined for their ability to probe the polymerization ...
Aβ toxicity to SHSY-5Y human neuroblastoma cells
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that results in the loss of memory, language deterioration, confusion, restlessness, and eventually destroyed cognition. It is characterized by an ...
Analysis of mitochondrial DNA insertions into a nuclear chromosome of the maize B73 line
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Mitochondrial DNA (mtDNA) is known to have integrated into the nuclear DNA of plants and animals. The purpose of this project is to investigate the on-going migration of mtDNA into the nuclear DNA of maize plants. Specific ...
The effect of caloric restriction on the mitotic rates of mice
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Caloric restriction has been shown to cause a number of biological changes in animals including the retardation of the aging process. Calorically- restricted animals show an average increase in life span of 30 - 50 %. In ...
A search for regulators of a yeast synaptojanin
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
The yeast S. cerevisiae expresses three synaptojanins: Inp51p, Inp52p, and Inp53p. These enzymes are characterized by two specific characteristics. They contain an inositol 5'-phosphatase and a polyphosphoinositide ...
The evolving technology of bio-printing
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Bio-printing is a novel method of tissue engineering that uses living cell spheroids as the 'bio-ink' and biocompatible gels as the 'bio-paper' with a three dimensional printer that deposits these aggregates into the gel ...
The effect of aryl substituted triamidoamine ligands on the structure of dioxo-molybdenum (VI) complexes
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Molybdenum is a known transition metal recognized for its crucial role as an active center for oxygen transfer in enzymes and has also been known to split dinitrogen. Experiments conducted during the internship period ...
Synthesis and binding studies of novel sigma receptor ligands
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Sigma receptors are binding sites that are found in the brain, in the endocrine and immune systems, and also in the lungs, kidneys, intestines, muscles and especially the liver. They are classified into two subtypes, sigma1 ...
Stroke risk factors and awareness study
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Cerebrovascular Accidents, also known as strokes, are the third leading cause of death in the United States. It is estimated that more than 275,000 people die from strokes every year (American Heart Association 2003). In ...
How the revolutionary thought of two West Indian intellectuals predicts and explains post-independence African problems
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Though most of Africa gained independence from European colonial rule by 1960, today the continent is still plagued by poverty, ignorance, corruption, internal conflict, and external control. These results are now clear ...
The synthesis of peptide-PNA conjugates
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
In two long term studies of non-Hodgkin's Lymphoma (NHL), the only clinical feature associated with a high relapse rate and treatment resistance is the presence of the B-cell lymphoma/leukemia-2(bcl-2) proto-oncogene in ...
Identifying Lepidopteran resistance within hcf mutants
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Southwestern corn borer (SWCB) and fall armyworm (FAW) feeding on maize causes extensive crop damage in the United States. Previous proteomic analysis comparing resistant and susceptible lines of maize indicates genes found ...
Quantitative trait loci for seminal root angle and number in the maize IBM population
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
In maize, seminal roots develop and the primary root system deteriorates as the plant matures. The seminal roots comprise the majority of the root system of the adult plant and give the plant stability against lodging. ...
Characterization of N gene homologs in Nicotiana species
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
We have developed a new variety of Nicotiana, N. edwardsonii var. Columbia, that can be used as a bridge plant to move virus resistance genes from N. glutinosa to N. clevelandii, and have made crosses between N. edwardsonii. ...
Development of conversation in toddlers: The role of maternal input
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
One of the most important human skills is the ability to engage in conversation. This includes our ability to initiate topics, take turns appropriately, and respond contingently to a partner's utterances. While we know ...
Mean value formulas for differential operators
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
The main goal of our research is to discuss Mean Value Formulas for solutions of partial differential equations of a certain form (see 1 below) where A is a symmetric, positive definite, real-valued matrix. Such equations ...
Effects of washings and treatments on the usefulness of hair as a biomarker
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Hair is a useful matrix for the analysis of many trace elements found in the human body. Studies show that hair can incorporate trace metals into its structure during the growth process. Hair is an attractive monitor because ...
Up-regulation of the P2Y2 receptor by cytokines in neuronal cells
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Alzheimer's Disease (AD) is characterized by inflammation and neurodegeneration in the brain due to the presence of extracellular amyloid beta (A β) plaques and neurofibrillary tangles. Microglial and astrocyte cells ...