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Longer Right Colon Withdrawal Time and Retroflexion Duration Significantly Increases Adenoma Detection Rate: A Randomized Controlled Trial at Three Endoscopy Centers
(University of Missouri--Kansas City, 2018)
Purpose
Detection of adenomas is the foundation of colorectal cancer screening utilizing
screening colonoscopies. Adenoma detection rate (ADR) is an increasingly utilized core
quality measure for colonoscopies. ...
Identification of Novel Regulatory Genes in Acetaminophen Induced Hepatocyte Toxicity by a Genome-Wide CRISPR/Cas9 Screen
(University of Missouri -- Kansas City, 2018)
Acetaminophen (APAP) is a commonly used analgesic responsible for over 56,000
overdose-related emergency room visits annually. A long asymptomatic period and limited
treatment options result in a high rate of liver ...
Association Between Myocardial Ischemia, Microvascular Function and Patient-Reported Angina
(University of Missouri -- Kansas City, 2019)
Prior studies have not found an association between myocardial ischemia and
measures of health status. Whether positron emission tomography (PET)-derived coronary
flow reserve (CFR) would be better correlated with ...
The Association of Socioeconomic Status with Mortality and Hospital Length of Stay in Patients with Parapneumonic Empyema
(University of Missouri -- Kansas City, 2018)
Background: Parapneumonic empyema is an uncommon but serious complication of
pneumonia. Anecdotal evidence suggests that the prevalence of empyema may be on the rise.
The aim of this study is to estimate the current ...
Risk of Expectant Management and Optimal Timing of Delivery in Low-risk Term Pregnancies: A Population-based Study
(University of Missouri -- Kansas City, 2018)
Introduction
The benefits of the current obstetric recommendation to avoid elective deliveries
before 39 weeks of gestation in pregnant women have been questioned by several authors.1
5 Multiple concerns such as ...
Comparison of Patient-Reported Angina with Provider Assigned Canadian Cardiovascular Society Angina Class Before and After Revascularization
(University of Missouri--Kansas City, 2016)
Background: The Canadian Cardiovascular Society (CCS) classification system for angina is a critical
determinant of revascularization appropriateness. A major limitation of CCS is that it rates
patients’ symptoms from ...
Effect of Angina Under-recognition on Treatment Escalation in Outpatients with Stable Ischemic Heart Disease
(University of Missouri--Kansas City, 2017)
Almost a third of outpatients with chronic coronary artery disease (CAD) report
having angina in the prior month, which is frequently under-recognized by their
cardiologists. Whether under-recognition is associated ...
Management, and Health Status Outcomes Of Obese Patients With Symptomatic Peripheral Artery Disease: Insight From The Portrait Registry
(University of Missouri -- Kansas City, 2018)
Obesity is present in 36.2%, 20.4 % and 29.0% of adults in the US, Netherlands and
Australia respectively. Obesity is a risk factor for cardiovascular disease and related
complications. The management and health status ...
Decisional Conflict in Peripheral Arterial Disease: Association with Treatment Choice and Health Status
(University of Missouri--Kansas City, 2017)
Background: Symptom relief in peripheral arterial disease (PAD) can be obtained by
invasive options such as endovascular stenting as well as exercise, and PAD medications.
Each of these options have their own risks and ...
Menstruation and Contraception Patterns of Female Adolescent Transplant Patients
(University of Missouri--Kansas City, 2017)
BACKGROUND
New data and guidelines support the use of contraception in adolescents on immunosuppressants, however, there is no data regarding base knowledge and attitude toward contraception in this particular patient ...
Use of National Electronic Health Record (EHR) Data Warehouse to Identify Inappropriate HbA1c Orders for Sickle cell Disease Patients
(University of Missouri--Kansas City, 2018)
The glycated Hemoglobin (HbA1c) test is one of the most important diagnostic
and prognostic strategies for monitoring diabetes. However, the clinical utility of this test
is questionable for sickle cell disease patients, ...
Impact of Systematizing the Evaluation of Patients with Acute Heart Failure Presenting to the Emergency Department
(2020)
The huge burden of acute heart failure (HF) on the emergency department (ED) warrants the need for a systemized method of management. The lack of a standardized care path for acute HF patients presenting to the ED has ...
Guideline-Directed Statin Therapy in Patients with New or Worsening Symptoms of Peripheral Artery Disease
(University of Missouri -- Kansas City, 2018)
Objective: The ACC/AHA cholesterol guidelines recommend patients with peripheral artery
disease (PAD) be treated with a moderate to high-intensity statin. The extent to which PAD
patients with new or worsening ...
Variability in Pricing of Generic Antipsychotic Medications Used in the Treatment of Schizophrenia at Community Pharmacies in the Kansas City Metropolitan Area
(University of Missouri -- Kansas City, 2018)
Studies examining variability in generic medication pricing at community
pharmacies have revealed conflicting results. No studies have examined variability in
costs of antipsychotic medications or if these costs vary ...
Mortality Risk Among Patients Who Present to Hospitals with Out-Of-Hospital Cardiac Arrest and ST-Elevation Myocardial Infarction
(2021)
In the emergent setting of an ST-elevation myocardial infarction (STEMI) presenting with an out-of-hospital cardiac arrest (OHCA), decisions for immediate coronary angiography are made when the likelihood of survival is ...
Thirty-Day Readmissions after Early versus Delayed Discharge after Uncomplicated Transcatheter Aortic Valve Replacement: Insights from the Nationwide Readmissions Database
(University of Missouri -- Kansas City, 2019)
Early discharge after transcatheter aortic valve replacement (TAVR) has generally
shown to be safe; however, studies have been limited to single centers or trial populations,
making their generalizability unclear. This ...
Evaluation of the Role of Adjunctive Corticosteroids in the Management of Children Hospitalized with Orbital Cellulitis
(University of Missouri--Kansas City, 2017)
Purpose/Objectives
Orbital cellulitis is an infection of the orbit that can lead to rare, but life-altering
complications. Previous studies have suggested that corticosteroids may improve recovery in
patients with ...
Are Functional Limitations Predictive of Use of Complementary and Alternative Medicine by Chronic Pain Patients?
(University of Missouri--Kansas City, 2017)
Chronic pain is an escalating problem in the United States, with a prevalence
of over 100 million people at an annual cost of $560 – 635 billion per year in medical
costs and lost productivity. Some of the consequences ...
Early Versus Delayed Tracheostomy in Mechanically Ventilated Patients With Chronic Obstructive Pulmonary Disease
(2020)
Background: Acute respiratory failure due to the acute exacerbation of chronic obstructive pulmonary disease (COPD) may need intensive care unit (ICU) admission and invasive ventilation that places COPD patients at a ...
Predicting Obstructive Coronary Artery Disease in Patients Undergoing Coronary Angiography for Stable Angina
(2021)
Accurately identifying the pre-test probability of obstructive coronary artery disease (CAD) in patients presenting with chest pain is key in determining the next steps in management. The Diamond-Forrester model, or an ...