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Now showing items 201-220 of 295
The impact of "July effect" on "failure to rescue" : do patients who undergo coronary artery bypass grafting at teaching hospitals face a selective disadvantage? [abstract]
(2010)
The new academic cycle in July is associated with the commencement of postgraduate medical education. Although this is presumed to be associated with poor patient outcomes, supportive evidence is limited for Cardiac surgery ...
Geographic distribution of Show Me Healthy Women providers and breast cancer incidence and mortality in Missouri counties [abstract]
(2010)
Breast cancer is the second most common cause of cancer death among US women. Regular mammography is the most effective method to reduce mortality. However, uninsured women face substantial barriers to receiving regular ...
Effects of statins on metabolic adaptations to aerobic exercise training : preliminary findings [abstract]
(2010)
Emerging evidence suggests statins, unlike exercise, may cause deleterious effects on skeletal muscle oxidative capacity and insulin sensitivity. The purpose of this study was to determine if daily statin therapy altered ...
Immediate versus delayed percutaneous coronary intervention for patients with non-ST elevation-acute coronary syndrome : a meta-analysis of randomised trials [abstract]
(2010)
Studies have indicated that an early invasive strategy is favorable over a selective invasive strategy for Non-ST segment elevation acute coronary syndromes (NSTE-ACS). However, there is no general consensus on precisely ...
Integrin-linked kinase : a potential player in ovarian cancer metastesis [abstract]
(2010)
Epithelial ovarian cancer (EOC) is the fifth leading cause of overall cancer death among American women. In 2008, 15,520 deaths were directly attributed to EOC, and an additional 21,650 cases were diagnosed. When EOC is ...
Evaluation of [99MTc]glucarate as a breast cancer imaging agent : bench to bedside [abstract]
(2010)
The use of [99mTc]glucarate has been reported as an infarct-avid agent with the potential for very early detection of myocardial infarction. [99mTc]glucarate has also been postulated as an agent for non-invasive detection ...
PGC-1[alpha] overexpression in primary hepatocytes increases fatty acid oxidation and mitochondrial content [abstract]
(2010)
The role of peroxisome proliferator-activated receptor-[gamma] coactivator-1[alpha] (PGC-1[alpha]) in increasing mitochondrial content and fatty acid oxidation (FAO) in skeletal muscle has been well described. Often, this ...
Retinal redox stress and ultrastructural remodeling in metabolic syndrome and diabetic retinopathy [abstract]
(2010)
Diabetic retinopathy is the major cause of blindness in the United States in the age group from 20-74. There are four traditional metabolic pathways involved in the development of diabetic retinopathy: increased polyol ...
Comparison of different strategies in parathyroid scintigraphy imaging [abstract]
(2010)
To retrospectively compare the various scintigraphic methods to discover the most accurate protocol for preoperative localization of single-gland disease, medical records of 710 patients, diagnosed with primary were reviewed. ...
Development of biospecimen sample preparation techniques for molecular imaging using ultra-high resolution mass spectrometry [abstract]
(2010)
Matrix assisted laser desorption ionization (MALDI) imaging is a technique which analyzes and maps the distribution of molecules in two-dimensional biospecimens, such as histological tissue sections. To-date, the classifications ...
Comparison of different strategies in parathyroid scintigraphy imaging in the setting of multi-gland hyperparathyroidism [abstract]
(2010)
Medical records of 140 patients, diagnosed with multigland primary, secondary or tertiary hyperparathyroidism were reviewed. Of those, 56 patients had complete preoperative parathyroid scintigraphy with subsequent surgical ...
Studying physician use and satisfaction with web-based treatment guides that incorporate patient information from the electronic medical record [abstract]
(2010-03)
Clinical decision support tools are important components of the electronic medical record. Previous studies have demonstrated that such tools can directly improve patient care outcomes and the performance of healthcare ...
This little piggy went running, that little piggy stayed home : a forelimb perspective of limb loading [abstract]
(2010-03)
Variation in mechanical loading is known to influence chondral modeling. However, the interaction between chondrocyte behavior, skeletal morphology, and ontogenetic variation in activity patterns are variably understood. ...
Utrophin up-regulation helps maintain normal cardiac geometry in a gene therapy model for Duhenne muscular dystrophy heart disease [abstract]
(2010-03)
Duchenne muscular dystrophy (DMD) is the most common childhood muscle wasting disease. DMD sufferers rarely survive past their mid-twenties succumbing to respiratory or heart failure. Skeletal and heart muscle pathology ...
Sudden cardiac death in a young man with massive left ventricular pseudoaneurysm
(2010-03)
Introduction: Left ventricular (LV) pseudoaneurysm (PA) is a known complication of myocardial infarction and rarely, mitral valve (MV) replacement surgery or endocarditis. PAs are prone to rupture with a 50% mortality rate ...
Transcription factors, 5'-TG-3'- ineracting factors (TGIF), regulates trichostatin-A mediated inhibition of corneal scarring [abstract]
(2010-03)
Purpose: Recently, we demonstrated that Trichostatin-A (TSA) inhibits transforming growth factor beta 1 (TGF 1)-induced fibrosis (haze) in rabbit cornea in vivo. However, the molecular mechanism of this process is still ...
Vocal dynamics in expressing emotions in classical, pop, and jazz styles of singing [abstract]
(2010-03)
Expressing emotions is one of the primary speech related functions of the larynx. Patients with Parkinson's disease have trouble in expressing emotions at linguistic and non linguistic (facial expression) levels. Understanding ...
Viability of chondrocytes embedded in agarose gel [abstract]
(2010-03)
Introduction: Arthritis affects a large portion of our population resulting in a significant expense with limited solutions and current treatment has limited options. The current research examines the viability of chondrocytes ...
Intrinsic high aerobic capacity protects against lipid induced hepatic insulin resistance [abstract]
(2010)
Hepatic steatosis is commonly linked to hepatic insulin resistance. However, recent studies have found that increased hepatic triacylglycerol (TAG) accumulation is not always associated with impaired hepatic insulin ...
177Lu radiolabeled peptides for breast cancer therapy [abstract]
(2010)
ErbB-2 is a type 1 receptor tyrosine kinase over-expressed on ~30% of breast cancers and is an attractive target for the development of new diagnostic and therapeutic agents. The ErbB-2 avid peptide KCCYSL, originally ...