Search
Now showing items 241-260 of 359
Topical Clear Aqueous Nanomicellar Formulations For Anterior And Posterior Ocular Drug Delivery
(2015-08-04)
The objective of this study was to develop a clear, aqueous drug loaded
nanomicellar formulation (NMF) for the back-of-the-eye delivery. Hydrophobic
drugs such as cyclosporine, resolvin analog (RX-10045), dexamethasone ...
An integrated approach for characterization of properties and mesostructure for FDM Ultem 9085
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The Fused Deposition Modeling (FDM) process is a layered prototyping technique used to build prototypes out of thermoplastic materials. It is currently ...
Near infrared fluorescent sensors for selective glucose recognition
(University of Missouri--Columbia, 2021)
With diabetes becoming a major health concern worldwide, it is growing clear that novel technologies are needed to monitor blood glucose in a manner that is continuous, real-time, and long-term --all while alleviating the ...
The role of hepatocellular eNOS in NAFLD development and hepatic mitochondrial adaptations to exercise
(University of Missouri--Columbia, 2020)
Whole body loss of endothelial nitric oxide synthase (eNOS) worsens hepatic mitochondrial function and exacerbates nonalcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) development and progression. However, the ...
Reparative dysfunction during muscle regeneration in Duchenne muscular dystrophy: therapeutic approaches to modulating the muscle environment and muscle stem cells
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Duchenne muscular dystrophy (DMD) is a lethal muscular dystrophy resulting from functional loss of the dystrophin protein, a critical sub-sarcolemmal ...
Conservation and divergence of reproductive phasiRNAs in flowering plants
(University of Missouri--Columbia, 2021)
Plant small RNAs (sRNAs) are important regulatory elements that fine-tune gene expression and maintain genome integrity by silencing transposons. They have critical roles in most pathways involved in plant growth and ...
Regulation of plant development in Arabidopsis
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The development of a complex organism, such as a plant, requires the function of multiple pathways that regulate various aspects of the developmental ...
Metabolically activated heterocyclic N-oxide compounds for killing and visualizing hypoxic cancer cells
(University of Missouri--Columbia, 2009)
Tirapazamine (TPZ) is currently undergoing a variety of phase I, II, and III clinical trials for the treatment of various human cancers. TPZ derives its medicinal activity by inducing DNA damage in poorly oxygenated tumor ...
MUtation, 1964
(University of Missouri--Columbia, 1964)
Yearbook for the University of Missouri--Columbia School of Medicine.
Hormonal and genetic control of leaf and vein development in maize
(University of Missouri--Columbia, 2022)
Grasses (Poaceae) have successfully colonized diverse terrestrial ecosystems and impacted human civilization by producing the bulk of world food supply. The grass leaf is distinct for having a sheathing base and strap-like ...
Volume change and swelling pressure of expansive clay in the crystalline swelling regime
(University of Missouri--Columbia, 2008)
A significant amount of research has been carried out to characterize expansive clay behavior from either microstructural or macrostructural perspectives; however, there exists a current gap in our knowledge about the basic ...
Campus columns, 1977 September - 1978 June
(University of Missouri--Columbia., 1977)
Volume 9 includes issues: Sept. 7, 1977 -- Sept. 21, 1977 -- Oct 9, 1977 – Nov. 16, 1977 -- Dec. 14, 1977 -- Jan. 11, 1978 -- Feb. 8, 1978 -- March 8, 1978 -- April 5, 1978 -- May 17, 1978 -- June 28, 1978
Campus columns, 1978 September - 1979 June
(University of Missouri--Columbia, 1978)
Volume 10, No. 1 - No. 11
HIV-1 5'UTR RNA structures: connections to infectious lifecycle and potential therapeutic applications
(University of Missouri--Columbia, 2021)
relevance in the HIV-1 infectious lifecycle. In this dissertation, we map the binding interface of HIV-1 5'UTR TAR RNA with INI1, a core component of the SWI/SNF eukaryotic chromatin remodeling complex. This is the first example of HIV-1 RNA surface...
Graduate school announcement, 1948-49
(University of Missouri, 1948)
Mizzou, volume 111, number 2 (2023 Winter)
(MU Alumni Association, University of Missouri, 2023)
An essential role in germline development for a P-granule associated novel protein in the model organism Caenorhabditis elegans and RNAi in the ubiquitous parasitic nematode Ascaris suum
(University of Missouri--Columbia, 2009)
The germline RNA helicases (GLHs) are constitutive components of P granules and important for fertility in C. elegans. Discovered as a GLH-1 partner, the P-granule associated novel protein (PAN-1) is important both in ...
High valent uranium dioxo and imido complexes : synthesis and structure
(University of Missouri--Columbia, 2008)
properties due to 5f/6d orbital involvement in multiple covalent bonding. The research discussed in this dissertation surveys the synthesis, isolation, and molecular and electronic structural characterization of uranyl(VI) and uranium(V)-imide complexes...
Studies on the physical properties and preservation of the North American pawpaw (Asimina triloba) fruit
(University of Missouri--Columbia, 2023)
The North American pawpaw (Asimina triloba) fruit is an annonaceous fruit that belongs in the same family as tropical fruits like soursop, cherimoya, atemoya, and others. Pawpaw is the only fruit in the Annonaceae family ...
Aptamers against viral proteins as a tool to answer biological questions
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] There are two experimental chapters in this dissertation in which the fundamental questions center around aptamers and viruses and how these two ...