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Aβ toxicity to SHSY-5Y human neuroblastoma cells
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that results in the loss of memory, language deterioration, confusion, restlessness, and eventually destroyed cognition. It is characterized by an ...
Imaging reticulospinal neurons in the lamprey brainstem using calcium indicator
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Imaging reticulospinal neurons in the lamprey brainstem using calcium indicator In the lamprey, a lower vertebrate, reticulospinal (RS) neurons in the brain are the output elements of the command system that activate spinal ...
Analysis of mitochondrial DNA insertions into a nuclear chromosome of the maize B73 line
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Mitochondrial DNA (mtDNA) is known to have integrated into the nuclear DNA of plants and animals. The purpose of this project is to investigate the on-going migration of mtDNA into the nuclear DNA of maize plants. Specific ...
The effect of caloric restriction on the mitotic rates of mice
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Caloric restriction has been shown to cause a number of biological changes in animals including the retardation of the aging process. Calorically- restricted animals show an average increase in life span of 30 - 50 %. In ...
A search for regulators of a yeast synaptojanin
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
The yeast S. cerevisiae expresses three synaptojanins: Inp51p, Inp52p, and Inp53p. These enzymes are characterized by two specific characteristics. They contain an inositol 5'-phosphatase and a polyphosphoinositide ...
The evolving technology of bio-printing
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Bio-printing is a novel method of tissue engineering that uses living cell spheroids as the 'bio-ink' and biocompatible gels as the 'bio-paper' with a three dimensional printer that deposits these aggregates into the gel ...
Conversion of waste corn cobs to activated carbons for natural gas (methane) adsorption
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Adsorbed Natural Gas (ANG) is an alternative energy source technology that uses micropores in adsorbent materials to store natural gas. Activated carbons, which are useful adsorbents with a highly porous form of carbon are ...
The effect of timber stand improvement practices on the abundance of Pileated Woodpeckers
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
The Pileated Woodpecker (Drycopulus pileatus) is a large woodpecker that requires large dead trees within a mature forest. I investigated how forest management practices affect the Pileated Woodpecker. Timber stand improvement ...
Functional analysis of nematode secreted proteins to devise innovative approaches for plant resistance against nematodes [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2007)
Approximately 1 billion dollars in soybean yield loss is caused annually in the US by a microscopic parasite known as the soybean cyst nematode (SCN; Heterodera glycines). My research is focused on studying cyst nematode ...
University of Missouri geotechnical experiment site [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2007)
The MU Geotechnical Experiment Site team is conducting laboratory testing on soil samples from a field site consisting of 9 bore holes ranging from a final depth of 20 to 50 foot below the surface. The purpose of this ...
Use of antisense oligonucleotides to enhance exon 7 incorporation in the pre-mRNA splicing of SMN2
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Spinal muscular atrophy (SMA) is a neurodegenerative disorder that is relatively common in humans and is caused by loss of the survival motor neuron 1 (SMN1) gene. SMA is the leading cause of hereditary infant mortality ...
A kinetic study of active site mutations in GDP-mannose dehydrogenase
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
In the human pathogenic bacterium Pseudomonas aeruginosa, GDP-mannose dehydrogenase (GMD) serves as a critical enzyme in the biosynthesis of alginate, a polysaccharide that functions as a protective coating against antibiotics ...
Natural variation in Arabidopsis thaliana: Molecular genetic architecture of stress tolerance under water deficit
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
The functional genomics tools available for studying Arabidopsis thaliana are a great resource for researchers trying to characterize and understand the genetic basis of natural variation. Genome wide transcript profiling ...
Uranium: The problem, or the solution?
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Uranium is of great importance as a nuclear fuel and is used to generate electrical power, produce isotopes, and to make weapons. The possibility of developing a realistic flow scheme for nuclear fuel reprocessing or ...
Do type I collagen defects that cause Osteogenesis Imperfecta result in an inherent muscle pathology? [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Osteogenesis imperfecta (OI) is a congenital connective tissue disorder characterized by decreased bone mineral density and increased bone fragility and susceptibility to fracture. In addition to skeletal fragility, patients ...
Effect of experimental forest treatments on gray treefrog (Hyla versicolor) habitat use [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Amphibian use of modified habitats has recently received more attention due to anthropogenic land-use patterns and the continued decline of species. We examined habitat use and abundance of gray treefrogs (Hyla versicolor) ...
Target test tube assembly process and design for the development of molybdenum-99 [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Molybdenum-99 (Mo-99) is used to create Tc-99m, a widely used nuclear medicine diagnostic imaging radioisotope. In an attempt to decrease the need for imported Mo-99, development of mechanical systems to efficiently prepare ...
The manifestation of death in Nathaniel Hawthorne's gothic fiction [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Nathaniel Hawthorne is one of the most popular authors of American literature during the 19th century. My research then investigates how Nathaniel Hawthorne's “Alice Doane's Appeal” as well as “The House of Seven Gables” ...
Race relationships in Aphra Behn's Oroonoko [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
A number of scholars classify Aphra Behn's Oroonoko as one of the first anti-slavery or abolitionist narratives. However, my research discusses the seemingly problematic nature of Behn's text because of her decision to ...
Growth of orthographic representations in children with LLD [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
One aspect of word learning from reading is knowledge of the orthographic representation of a word. Children with language-learning disabilities (LLD) might be expected to have greater difficulties than peers acquiring ...