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Now showing items 21-40 of 115
Site-specific genomic (SSG) and random domain-localized (RDL) mutagenesis in yeast
(2004-04-16)
Abstract
Background
A valuable weapon in the arsenal available to yeast geneticists is the ability to introduce specific mutations ...
TILLING to detect induced mutations in soybean
(2008-01-24)
Abstract
Background
Soybean (Glycine max L. Merr.) is an important nitrogen-fixing crop that provides much of the world's protein ...
One-year health status outcomes of unstable angina versus myocardial infarction: a prospective, observational cohort study of ACS survivors
(2007-09-12)
Abstract
Background
Unstable angina (UA) patients have lower mortality and reinfarction risks than ST-elevation (STEMI) or non-ST elevation myocardial infarction (NSTEMI) patients ...
Gene selection for classification of microarray data based on the Bayes error
(2007-10-03)
Abstract
Background
With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a ...
FEPI-MB: identifying SNPs-disease association using a Markov Blanket-based approach
(2011-11-24)
Abstract
Background
The interactions among genetic factors related to diseases are called epistasis. With the availability of ...
TILLING to detect induced mutations in soybean
(2008-01-24)
Abstract
Background
Soybean (Glycine max L. Merr.) is an important nitrogen-fixing crop that provides much of the world's protein ...
Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor
(2012-06-14)
Abstract
Background: Altered immune function during ageing results in increased production of nitric oxide (NO) and other inflammatory mediators. Recently, we have reported that NO production was inhibited ...
ART adherence changes among patients in community substance use treatment: a preliminary analysis from MACH14
(2012-10-11)
Abstract
Background
Opiate substitution treatment has been associated with better adherence to lifesaving antiretroviral medications, but the impact of other substance abuse treatment on ...
delta-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens
(2011-02-28)
Abstract
Background
Chronic, low-grade inflammation provides a link between normal ageing and the pathogenesis of age-related diseases. A series of in vitro tests confirmed the strong anti-inflammatory activities ...
Neuroprotective effect of peroxiredoxin 6 against hypoxia-induced retinal ganglion cell damage
(2010-10-05)
Abstract
Background
The ability to respond to changes in the extra-intracellular environment is prerequisite for cell survival. Cellular responses to the environment include elevating defense systems, such as the ...
Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female mice.
(2010-12-16)
Abstract
Background
Inflammation has been implicated in cardiovascular disease, and the important role of proteasomes in the development of inflammation and other macrophage functions has been demonstrated. ...
Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female mice.
(2010-12-16)
Abstract
Background
Inflammation has been implicated in cardiovascular disease, and the important role of proteasomes in the development of inflammation and other macrophage functions has been demonstrated. ...
Autonomous growth potential of leukemia blast cells is associated with poor prognosis in human acute leukemias
(2009-12-29)
Abstract
We have described a severe combined immunodeficiency (SCID) mouse model that permits the subcutaneous growth of primary human acute leukemia blast cells into a measurable subcutaneous nodule which may be followed ...
The role of Candida albicans homologous recombination factors Rad54 and Rdh54 in DNA damage sensitivity
(2011-09-27)
Abstract
Background
The fungal pathogen Candida albicans is frequently seen in immune suppressed patients, and resistance to one of the most widely used antifungals, fluconazole (FLC), can evolve rapidly. In recent years ...
HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-kappaB pathway and can be silenced by gp120-specific siRNA
(2010-12-29)
Abstract
Background
The exact mechanism underlying HIV-associated neurocognitive disorders still remains largely unresolved. However, viral genes (for example gp120 and tat) and their effect on cytokine/chemokine ...
HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-kappaB pathway and can be silenced by gp120-specific siRNA
(2010-12-29)
Abstract
Background
The exact mechanism underlying HIV-associated neurocognitive disorders still remains largely unresolved. However, viral genes (for example gp120 and tat) and their effect on cytokine/chemokine ...
Factors influencing patient willingness to participate in genetic research after a myocardial infarction
(2011-06-15)
Abstract
Background
Achieving 'personalized medicine' requires enrolling representative cohorts into genetic studies, but patient self-selection may introduce bias. We sought to identify characteristics associated ...
A unified phylogeny-based nomenclature for histone variants
(2012-05-31)
AbstractHistone variants are non-allelic protein isoforms that play key roles in diversifying chromatin structure. The known number of such variants has greatly increased in recent years, but the lack of naming conventions ...
Tandem repeat regions within the Burkholderia pseudomallei genome and their application for high resolution genotyping
(2007-03-30)
Abstract
Background
The facultative, intracellular bacterium Burkholderia pseudomallei is the causative agent of melioidosis, a ...
An informatics search for the low-molecular weight chromium-binding peptide
(2004-12-16)
Abstract
Background
The amino acid composition of a low molecular weight chromium binding peptide (LMWCr), isolated from ...