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Cubic and spherical nanoparticles for detection and therapy of cancer
(University of Missouri--Columbia, 2016)
Cancer is the leading cause of high mortality rates. Cancer patients require advanced treatment due to lack of early prevention and diagnosis. Moreover, progression of the disease is unpredictable and personalized therapy ...
Knee contact force prediction during a step-up task using a subject specific musculoskeletal model with anatomical knee
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Better understanding of knee mechanics can aid in injury prevention and rehabilitation. Multi-body computational models can be used to better understand ...
Investigation of supercritical water processing of biomass : study of high pressure separation
(University of Missouri--Columbia, 2016)
Global warming is caused by greenhouse gases such as CO2, CH4, NOx, and SOx. CO2 makes up about 80% (by mass) of greenhouse gas emitted by human activities. Therefore, CO2 emission plays a significant role in global warming. ...
Design and characterization of a hand-held, waveguide-mediated, optoacoustic imaging probe for analyzing burn wounds
(University of Missouri--Columbia, 2018)
Clinicians correctly diagnose only [about]66% of burn wounds, which may be in part due to the qualitative methods commonly employed for burn assessment. This often results in over diagnoses, which may lead to unnecessary ...
Single nucleotide polymorphism (SNP) discriminations by nanopore sensing
(University of Missouri--Columbia, 2018)
Single Nucleotide Polymorphisms (SNPs) are a common type of nucleotide alterations across the genome. A rapid but accurate detection of individual or SNP panels can lead to the right and in-time treatments which possibly ...
In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds
(University of Missouri--Columbia, 2018)
Natural materials have been processed and utilized as scaffold materials in the field of tissue engineering for many years. One natural material often utilized is collagen since it is the main structural protein in mammalian ...
Between-row mower design for weed control in organically grown no-till soybeans
(University of Missouri--Columbia, 2018)
Weeds are a major challenge in organic no-till soybean production. They impair crop growth and result in yield loss. Innovative weed control methods need to be developed and experimented with in organic no-till agriculture ...
Evaluating removal of nutrients, volatile organic compounds, and nicotine by bioretention soil mixtures with biochar amendment
(University of Missouri--Columbia, 2016)
Urbanization results in reduced infiltration contributing to potential urban flooding and stormwater contaminants. Urban stormwater pollutants, including total suspended solids (TSS), nutrients, heavy metals, oil and grease ...
Imaging fiber orientation in articular cartilage using optical polarization tractography
(University of Missouri--Columbia, 2016)
Articular cartilage plays a vital role in providing a low-friction surface between the bones of joints. This mechanical function is highly related to the special collagen organization in cartilage, especially in the ...
Paraxial application of auxiliary devices with waveguide mediated laser irradiation for applications in medical biophotonics
(University of Missouri--Columbia, 2017)
Laser-based medical applications offer minimally-invasive alternatives to traditional procedures; however, the simplistic method of open-air laser transmission poses ocular hazards and negative side effects, along with a ...
Fabrication and characterization of a plasmonic grating platform for enhanced fluorescence biosensor applications
(University of Missouri--Columbia, 2016)
Surface plasmon resonance (SPR) research has grown substantially over the past several years and led to many substantial discoveries in nanotechnology. SPR is a phenomenon where light can be coupled to the interface between ...
Accurate DNA microsatellite and microRNA detection with a biological nanopore
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Nanopore-based detection has been used in many genetic, epigenetic, proteomic, and bio-mechanism studies. In this report, we introduced two ...
Design and synthesis of targeted NIR fluorescent nanoparticles for bio-imaging
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Breast cancer is the second most common cancer, and the chance that a woman will die from breast cancer is 2.6%. One in 8 women develop ...
The impact of neuronal Nampt on motor function of mice
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Nicotinamide phosphoribosyltransferase (Nampt), also named visfatin and pre-B cell colony-enhancing factor (PBEF), is the rate-limiting enzyme converting ...
Imaging 3D tissue fiber organization using optical polarization tractography
(University of Missouri--Columbia, 2017)
Optical polarization tractography (OPT) is a new imaging technology developed based on an advanced Jones matrix implementation of polarization-sensitive optical coherence tomography (PSOCT). OPT can acquire high-resolution, ...
Development of a composite acellular tissue graft for musculoskeletal tissue engineering
(University of Missouri--Columbia, 2015)
A composite acellular tissue graft comprised of decellularized tendon conjugated with nanomaterials has been developed for musculoskeletal tissue engineering applications. The focus of this dissertation is on the development ...
Rapid detection and characterization of mycobacteria using microchannel electrical impedance spectroscopy
(University of Missouri--Columbia, 2017)
The presence of virulent, pathogenic bacteria in our body, food, water and other consumables is harmful and causes enormous economic and personal losses. Here we will be looking at developing a platform technology that can ...
Development of a multispectral sensor for crop canopy temperature measurement
(University of Missouri--Columbia, 2017)
The Multispectral System for Imaging of a Crop Canopy (MSICC) that combines a miniature long wavelength infrared (LWIR) camera with a visible camera was developed to capture a field of view and derive a plant specific ...
Structure/function studies of CFTR's pore-forming domain reveal evolutionary divergence between CFTR and ABC transporters
(University of Missouri--Columbia, 2015)
Cystic Fibrosis Transmembrane conductance Regulator (CFTR) is the culprit behind Cystic Fibrosis (CF), a genetic disease highly occurs among Caucasians. Studying the structure/function of CFTR chloride channel not only ...
Peptide nanoconjugates for tissue diagnostics and molecular imaging
(University of Missouri--Columbia, 2016)
The rise of targeted therapy in cancer treatment has created a strong need for characterization of a patient's tumor before receiving treatment. Many effective cancer drugs are now being targeted to specific proteins present ...