Search
Now showing items 21-40 of 114
Identifying substrate proteins for GAN1 and Keap1
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
GAN1 and Keap1 are proteins characterized by a N-terminal BTB domain and a C-terminal Kelch repeat domain. Both of these domains are protein-protein interaction domains, suggesting that these BTB-Kelch proteins form signaling ...
The effects of sensitization on habituation using the olfactory jump reflex in Drosophila
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Memories can arise from simpler habituation and sensitization training as well as associative classical conditioning. However, in a complex environment, animals receive sensory cues in a fashion that can be more accurately ...
The effects of oncogenic Ras on the ocular lens
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Ras is a small GTP-binding protein in the signal transduction machinery. In most cell types, activation of Ras by growth factors is essential for normal cell proliferation. A mutation in the Ras gene can lead to a constitutive ...
Therapy of experimental allergic encephalomyelitis under circumstances relevant to human multiple sclerosis
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Experimental allergic encephalomyelitis (EAE) is an inflammatory disease of the central nervous system (CNS) that resembles human multiple sclerosis (MS). EAE and MS develop when proteins of the myelin sheath that covers ...
Offspring sex ratio varies with maternal condition in mice
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Field and laboratory animal studies have demonstrated that maternal body condition can directly cause adjustments in offspring sex ratio. A mother's condition is affected by a variety of environmental and endogenous factors, ...
A multicopy suppressor screen in yeast to look for negative regulators of Ser13 phosphorylation-based trafficking to the pre-vacuolar compartment
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Resident membrane proteins of the yeast trans-Golgi network (TGN) frequently cycle between the TGN and both the early and late (prevacuolar) endosomal compartments. The model yeast TGN protein, A-ALP, which contains the ...
Isolation of TFIIIC102 in Arabidopsis thaliana to better understand transcription
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
at TFIIIC protein interactions shall provide some insight to the methods and regulation of transcription over the course of much long-term research. TFIIIC consists of six subunits that all work together to carry out the proper transcription of genetic...
Natural variation in Arabidopsis thaliana: Molecular genetic architecture of stress tolerance under water deficit
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
The functional genomics tools available for studying Arabidopsis thaliana are a great resource for researchers trying to characterize and understand the genetic basis of natural variation. Genome wide transcript profiling can simultaneously monitor...
What's in a worm; Uncovering polymophisms in soybean cyst nematode parasitism genes that correlate with virulence
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
soybean plants. Of particular concern, however, is that genetically diverse field populations of SCN have shown the ability to overcome current sources of resistance. Previous research has confirmed that parasitism genes expressed in esophageal gland cells...
Expression of aT4g27260/GH3-5/GH3a studied with in situ hybridization
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Tropisms, the responses of plants to external stimuli, have been studied as important evolutionary adaptations and as possible areas of future advantageous genetic manipulation. The goal of our current research is to identify targets of NPH4/ARF7...
Radiopharmaceutical research: Coordination of rhenium to tetradentate schiff base ligands
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Radiopharmaceuticals, drugs consisting of a radionuclide, are very useful in both the diagnostic and therapeutic treatment of cancer. The radiopharmaceuticals that were researched are composed of Re radioisotopes (Re-186; Re-188), which are very...
Uranium: The problem, or the solution?
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
is one that the Chemistry Department at MU consistently looks into. One way to better optimize waste extraction is to possibly bind two separate functional groups to uranyl(VI) [UO22+] so that the reactions will occur selectively. The product of interest...
A study of wireless sensor networks with focus on node localization
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Due to research in low-power, cheap wireless communications, Wireless Sensor Networks (WSN) has become one of the most exciting new fields of interest within computer science and engineering. Just as the Internet has made data readily available...
A comparative study of commercially synthesize immobilized pH gradient (IPG) strips for two-dimensional electrophoresis
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Two-dimensional electrophoresis (2-DE) is a widely used technique for resolving complex protein mixtures. The resurgence in this technique can be attributed to the contemporary approach for isoelectric focusing, which ...
Comparative analyses of NA genome in Zea maize
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Mitochondrial genomes are perhaps the most unusual sequences to annotate, due to the common characteristic of expedient change within the genome. Only six (mtDNA) genomes have been sequenced. It has been observed that ...
Won't you be my neighbor? An analysis of the effect of density on floral and nectar traits in Nicotiana alata
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
It has been shown that heritable, genetic variability can change in response to different environmental conditions (Hoffmann and Merila 1999) and also that some plants can sense proximate neighbors and change their growth ...
A computational model for genetically inherited depression
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
for this model was melancholic unipolar. The model was constructed from information gathered from research literature related to the brain, depression, and neuroscience. The precursors for melancholic MDD are polymorphisms of alleles that code for serotonin (5-HT...
Organization of the command system in the lamprey brain that initiates locomotor behavior
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
(DLM); and RS neurons (Paggett et al. 2004). Other experiments suggest the following organization for the command system: RLR VMD & DLM RS neurons à spinal CPGs In the present study, various lesions were made in the brain to interrupt some...
Cell-matrix interaction in tissue patterning
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
-2869, 2004....
Effect of baicalein on regulation of a phase II enzyme in human prostate cancer cell line (PC-3)
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Prostate cancer is an excellent candidate disease for chemo prevention because it is typically diagnosed in elderly males, therefore even a modest delay in the neoplastic development achieved through pharmacological or nutritional intervention could...