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Now showing items 21-35 of 35
Biologically relevant chemistry of sulfur heterocycles : from redox regulation of PTP1B to the biological activity of s-deoxy leinamycin
(University of Missouri--Columbia, 2008)
Protein tyrosine phosphatase 1B (PTP1B) is an important member of protein tyrosine phosphatase (PTPs) family that shares a conserved catalytic cysteine thiol residue. PTP1B acts as a negative regulator of insulin mediated ...
Oxidative DNA damage by 1-hydroxyphenazine, virulence factor of Pseudomonas aeruginosa : towards a molecular understanding of the bacterial virulence factor 1-hydroxyphenazine
(University of Missouri--Columbia, 2008)
1-Hydroxyphenazine is a secondary metabolite and virulence factor of Pseudomonas aeruginosa. This organism colonizes the airways of the patients of cystic fibrosis and causes progressive destruction of the airways. It is ...
A study of bacterial cellulose confined ionic liquid and deep eutectic solvent gel materials
(University of Missouri--Columbia, 2020)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Pollutants have become more prevalent in the air, water, and ground, necessitating the development of technologies that would help, limit, ...
Production of high specific activity rhenium-186 for radiotherapeutic applications and reformulation of a novel liquid brachytherapy agent
(University of Missouri--Columbia, 2022)
The continued development of methods for the production and separation of high specific activity (HSA) rhenium-186 (t1/2 = 90.64 h, Eb-ave = 359 keV (71 percent), 306 keV (22 percent)) would largely increase its use as a therapeutic analogue...
Anion and solvent influences on the self-assembly of copper(I) coordination solids
(University of Missouri--Columbia, 2005)
and the reaction conditions involved will be discussed. This presentation will be divided into four major sections. The first section covers an in-depth look at those structural variances found among the copper(I) coordination solids synthesized using 4,4...
Radionuclide production and separation techniques for radiopharmaceutical development and nuclear waste processing
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] With increasing cancer incident rates and advancements in nuclear medicine, the demand for optimizing pathways to produce radionuclides or investigating ...
Investigation of the thermostability and activity of biomolecules in bio-friendly deep eutectic solvents
(University of Missouri--Columbia, 2023)
The solvent environment of a biomolecule is critical to its optimal performance in various scenarios, including biocatalysis, drug delivery, therapeutics, and biosensing. This dissertation mainly discusses the implementation ...
A comparison of some methods of estimating radium
(University of Missouri--Columbia, 1914)
The quantitative determination of the small amounts of radium present in the atmosphere, spring waters, minerals and rocks involves two steps: (1) The quantitative separation of the radium emanation in a known weight of ...
Structural supramolecular constructs of spheres and tubes
(University of Missouri--Columbia, 2006)
revealed through the use of p-xylene.The third project investigated the interactions between nickel macrocycles and single walled carbon nanotubes. The final project took supramolecular hexamers from the cup-shaped pyrogallol[4]arene and produced large...
An evaluation of the need for critically refined purification procedures in fluorescent carbon dot syntheses : the ramifications of the ubiquitous presence of reaction by-products on quenchometric and light harvesting applications
(University of Missouri--Columbia, 2021)
Fluorescent carbon dots constitute a novel and intriguing class of nanocarbons that display unique optical properties and can be purportedly generated from virtually any carbon-containing source. For example, the thermal ...
Characterizing and understanding self-assembling, nanocapsule host-guest systems
(University of Missouri--Columbia, 2010)
Supramolecular, self-assembled nanocapsules have been shown to be capable of entrapping fluorescent guests. Previous solid- and solution-state research, focusing on hydrogen-bonded C-alkylpyrogallol[4]arenes (PgC6)nanocapsules, have shed light...
Determination and analysis of multiphoton excitation emissive species.: I,: Emission of PAHS in acidic medium,: II,: Multiphoton emission of possible PDT agents
(University of Missouri--Columbia, 2005)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The exploitation of ultrafast laser properties has been recently increasing. Recent research in this lab demonstrated the ability of femtosecond pulses ...
LC-MS/MS method development for quantitative analysis of cyanogenic glycosides in elderberry and lipid peroxidation products in mice
(University of Missouri--Columbia, 2021)
for its role in mediating neurological functions. Besides the source of many oxylipins with pro-resolving properties, DHA also undergoes peroxidation, producing 4-hydroxyhexenal (4-HHE), although its function remains elusive. Despite wide dietary...
Probing supramolecular assemblies via fluorescent reporter molecules
(University of Missouri--Columbia, 2007)
-alkylpyrogallol[4]arenes, PgC₆, nanocapsules in the solution. Nanocontainers of PgC₆ were self-assembled from six Pg building blocks, enclosing over 1200 Å3 of space. Steady-state and dynamic fluorescence spectroscopic techniques were used to interrogate...
Oxidative molecular layer deposition of redox-active thin-film polymers
(University of Missouri--Columbia, 2022)
Thin film materials research for a more sustainable future is growing rapidly and new techniques for depositing these films are beginning to surface. One such technique is highlight in this body of work using gaseous ...