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Skeletal Muscle - Bone Crosstalk Regulating Osteocyte Function [abstract]
(2010-03)
Osteocytes are thought to be the primary cell in bone that responds to mechanical loading and the traditional view is that skeletal muscle's role relative to bone is in the application of those loads. We have hypothesized ...
Cancer stem cells in malignant peripheral nerve sheath tumor: Biology and therapeutic ramifications [abstract]
(2010-03)
Although monoclonal in origin, most tumors appear to contain heterogeneous populations of cancer cells. One possible explanation of this tumor heterogeneity is that human tumors are not merely monoclonal expansions of a ...
Temporal trends in the management of severe hyperglycemia among patients hospitalized with acute myocardial infarction [abstract]
(2010)
Background: Elevated blood glucose (BG) is associated with an adverse prognosis in acute myocardial infarction (AMI) patients. While guidelines recommend insulin therapy to lower markedly elevated BG in AMI patients, it ...
Maternal exercise during pregnancy and the influences on cardiac autonomic control [abstract]
(2010)
Background: Our previous research found decreased fetal heart rate (fHR) and increased heart rate variability (HRV) as a result of regular maternal aerobic exercise. These results suggest exposure to exercise throughout ...
Antitumor withanolides from Withania somnifera [abstract]
(2010)
Surgery, University of Kansas Medical Center, Kansas City, Kansas 66160
Withania somnifera L. Dunal (Solanaceae) is an Indian plant commonly known as “ashwagandha”. This traditional plant has been used in Ayurvedic medicine ...
Innovation, Inspiration, and Insulation: Practical Legal Measures to Protect Technology
(2010-03)
The demand for new technologies is driving innovation worldwide, particularly in the fields of life sciences and biotechnology. Intellectual Property is the life blood of many life sciences and biotechnology companies. Protecting the IP...
Early Cancer Screening with Pteridines as Biomarkers
(2010-03)
. The detailed experimental conditions will be presented at the life science summit. After analysis of over 60 urine samples from cancer patients, we also discovered that two chemical components exist only in the urine of cancer patients but are not present...
The Vision Research Center of Kansas City
(2010-03)
The Vision Research Center was founded as and is a well established collaboration of several of UMKC schools and Kansas City Medical Centers and thus offers an unprecedented interdisciplinary synergy with a unified goal: ...
Derivation and characterization of LIF and FGF2 dependent Porcine Induced Pluripotent Stem Cells [abstract]
(2010-02)
. Currently, the ability of LIF-piPSC to give rise to teratoma and chimeras is under investigation. Supported by Missouri Life Sciences Board Grant 00022147 and NIH grant HD21896....
Biomaterials for Tissue Repair and Regeneration at Missouri S&T
(2010-03)
Biomaterials are critically important to future developments in the life sciences. They provide a backbone for biomedical research in academia and industry, and are a key component of reconstructive medical and dental research as well as patient...
Shock Wave Based Cell Transfection and Fluorescent Organosilicate Nanoparticles for Targeted Drug Delivery [abstract]
(2010)
Nanotechnology is a multidisciplinary field that has applications in life sciences, alternative energy, national defense, and electronics. In the field of medicine, nanotechnology may enable intelligent drug delivery using multifunctional...
Public-Private Collaborations to Promote Adult Literacy
(2010-03)
. Adapting educational materials is an appropriate short-term intervention. But these women wanted and needed much more. Low literacy negatively impacts the quality of an individual's entire life, not just health. Examples of life tasks requiring literacy...
Experiences in Patenting, Licensing and Commercialization of Radiopharmaceuticals
(2010-02)
three different approaches in developing corporate agreements that were successful in translating MU life sciences research into radiopharmaceuticals that are for use as diagnostic and therapeutic applications in human patients....
Cofactor Genomics: A Sequencing Service Company Emerges from the Technology Development Laboratory
(2010-03)
, evaluate and develop both wet-lab and computational applications for emerging Next-Generation sequencing technology platforms. Their experience began with beta testing the 454 Life Sciences (now Roche) GS 20, continued with beta testing the first serial...
Transgenic and Gene-Targeting Facility
(2010-03)
The Transgenic and Gene-Targeting Facility at the University of Kansas Medical Center is located in the newly constructed Kansas Life Sciences Innovation Center on the KUMC campus. The mission of the Transgenic Facility is to provide services...
A genetic linkage map of the fungus Phycomyces blakesleeanus
(2010-03)
of point mutations in furA and lysA genes that flank madD and madE, respectively. Additionally, using the carRA and carB genes as a starting point, the DNA regions near the madI gene have been found and the adjacent carS gene identified....
An Intelligent Online System for Enhanced Recruitment of Patients for Clinical Research
(2010-03)
The recruitment and retention of subjects for clinical research has been identified as one of the bottlenecks in the development of new drugs and treatments by the healthcare industry. The Kansas City Area Life Sciences Institute has been...
Science Outreach and Informal Science Education-Programs and Partnerships [abstract]
(2010-02)
over 145 presentations with approximately 18,000 total attendees. Science Talks to You (STTY) is SMS's new off-campus offshoot. Like SMS, STTY will feature direct engagement between established scientists and the public, but in venues around Missouri...
Are there leaks in your product pipeline?
(2010)
professional statistician. The University of Missouri System has statisticians on several campuses. There are graduate programs at the University of Missouri, UMKC and Missouri University of Science and Technology. Graduate students are available...
Comparative Ophthalmology - scientific discovery and innovation create synergies for veterinary and human medicine
(2010-03)
discoveries in comparative ophthalmology. Some examples of new technologies being developed for commercialization in Missouri will be highlighted. Specifically, advancements in our ability to observe cellular structure and function of the eye and visual...