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Now showing items 21-40 of 402
Is megestrol acetate safe and effective for malnourished nursing home residents?
(Family Physicians Inquiries Network, 2018)
Q: Is megestrol acetate safe and effective for malnourished nursing home residents? A: no. Megestrol acetate (MA) is neither safe nor effective for stimulating appetite in malnourished nursing home residents. It increases ...
Apolipoproteins for Cardiovascular Risk Assessment
(Family Physicians Inquiries Network, 2014)
Clinical Question: Is measurement of apolipoproteins better than traditional lipid measurements for predicting cardiovascular risk? Evidence-Based Answer: Measurement of apolipoprotein B and apolipoprotein A-I is no better than traditional lipid...
Do annual pelvic exams benefit asymptomatic women who receive regular Pap smears?
(Family Physicians Inquiries Network, 2015)
Q: Do annual pelvic exams benefit asymptomatic women who receive regular Pap smears? Evidence-based answer: No evidence exists to support a clinical benefit from annual pelvic examinations for asymptomatic women who receive Pap smears every 3 to 5...
How well do antivirals shorten genital herpes pain duration?
(Family Physicians Inquiries Network, 2015)
, and using ice packs or taking warm baths (SOR: C, expert opinion). Evidence for using complementary and alternative medicine to treat genital herpes is lacking or conflicting [SOR: C, narrative review of clinical trials]....
What's the best approach to diagnosing food allergies in infants?
(Family Physicians Inquiries Network, 2010)
A well-designed oral food challenge (OFC) is the most reliable diagnostic test for infants whose clinical history and physical examination suggest a specific food allergy (strength of recommendation [SOR]: C, consensus guidelines)....
Do antibiotics shorten symptoms in patients with purulent nasal discharge?
(Family Physicians Inquiries Network, 2012)
For most patients with purulent nasal discharge, antibiotics don't decrease symptom duration; they do increase adverse events (strength of recommendation [SOR]: A, 3 meta-analyses and 2 randomized controlled trials [RCTs]). ...
How can we minimize recurrent ankle sprains?
(Family Physicians Inquiries Network, 2011)
Using external ankle supports during physical activity significantly reduces the likelihood of primary and secondary sprains (strength of recommendation [SOR]: A, systematic review). Proprioception rehabilitation substantially ...
Which treatments help women with reduced libido?
(Family Physicians Inquiries Network, 2013)
Several treatments produce modest, but statistically significant, clinical increases in sexual desire and function in women. The testosterone transdermal patch improves hypoactive sexual desire disorder (HSDD) in postmenopausal women (strength...
What are the benefits and risks of inhaled corticosteroids for COPD?
(Family Physicians Inquiries Network, 2014)
) and statistically, but not clinically, improve quality of life (QOL) (strength of recommendation [SOR]: B, meta-analyses of heterogeneous studies). However, ICS have no mortality benefit and don't consistently improve forced expiratory volume in 1 second (FEV1) (SOR...
Do venlafaxine and gabapentin control hot flashes in women with a history of breast cancer?
(Family Physicians Inquiries Network, 2012)
Venlafaxine reduces hot flashes more than placebo in women with a history of breast cancer; adverse effects include dry mouth and constipation (strength of recommendation [SOR]: B, randomized clinical trials [RCTs] with heterogeneous outcomes...
Do A-fib patients continue to benefit from vitamin K antagonists with advancing age?
(Family Physicians Inquiries Network, 2019)
Q Do A-fib patients continue to benefit from vitamin K antagonists with advancing age? Evidence-based answer: yes, patients with atrial fibrillation who are between the ages of 50 and 90 years continue to benefit from ...
Do NSAIDs impede fracture healing?
(Family Physicians Inquiries Network, 2011)
Nonsteroidal anti-inflammatory drugs (NSAIDs) don't appear to impair clinical fracture healing (strength of recommendation [SOR]: B, inconsistent evidence from a randomized controlled trial [RCT] and retrospective studies). Even though animal...
Human parathyroid hormone for treating osteoporosis
(Family Physicians Inquiries Network, 2012)
Human parathyroid hormone should be used in patients with severe osteoporosis to decrease the rate of vertebral and nonvertebral fractures. (Strength of Recommendation [SOR]: A, based on a systematic review and randomized ...
How can we effectively treat stress urinary incontinence without drugs or surgery?
(Family Physicians Inquiries Network, 2014)
on SUI symptoms, and produces no clinically meaningful improvement in QOL (SOR: B, heterogeneous RCTs with conflicting results). Vaginal cones don't increase continence or QOL (SOR: B, 2 RCTs with methodoligic flaws)....
Medications for weight loss in patients with Type 2 diabetes mellitus
(Family Physicians Inquiries Network, 2012)
Fluoxetine (Prozac) and orlistat (Xenical) produce modest short-term weight loss, but their long-term benefits are unclear and their safety is uncertain. (Strength of Recommendation [SOR]: B, based on a meta-analysis of ...
Management of ADHD in preschool-aged children
(Family Physicians Inquiries Network, 2013)
Behavior therapy interventions, such as parent training, are first-line treatment for ADHD in preschool-aged children (three to five years of age). (Strength of Recommendation [SOR]: B, based on a systematic review of a ...
Exercise for the Treatment of Knee Osteoarthritis
(Family Physicians Inquiries Network, 2011)
Regular exercise reduces osteoarthritic knee pain and improves functioning. (Strength of Recommendation: A, based on systematic reviews.) Aerobic and strength-training exercises, including land- and water-based exercises, ...
Treatment of HSV infection in late pregnancy
(Family Physicians Inquiries Network, 2012)
Pregnant women with a primary or recurrent episode of genital HSV infection who are later than 36 weeks of gestation should be treated with acyclovir (Zovirax) or valacyclovir (Valtrex) for viral suppression. (Strength of ...
Which oral antifungal works best for toenail onychomycosis?
(Family Physicians Inquiries Network, 2013)
Terbinafine, 250 mg daily for 12 to 16 weeks, produces higher clinical cure rates than either pulsed-dose itraconazole or weekly fluconazole (strength of recommendation [SOR]: A, multiple randomized controlled trials [RCTs]). Daily oral dosing...
Antidepressant Use During Pregnancy
(Family Physicians Inquiries Network, 2011)
There are no studies that have shown any antidepressant to be absolutely safe for use during any stage of pregnancy. The use of selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants (TCAs) during ...