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Gene selection for classification of microarray data based on the Bayes error
(2007-10-03)
Abstract
Background
With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a ...
Gene selection for classification of microarray data based on the Bayes error
(2007-10-03)
Abstract
Background
With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a ...
Motivational Interviewing for encouraging quit attempts among unmotivated smokers: Study protocol of a randomized, controlled, efficacy trial.
(2012-06-19)
, smoking characteristics, and smoking outcomes. Participants who decide to quit are provided with a self-help guide to quitting, help with a quit plan, and free pharmacotherapy. The primary outcome is self-report of one or more quit attempts lasting...
Regional pulse wave velocities and their cardiovascular risk factors among healthy middle-aged men: a cross-sectional population-based study
(2014-01-13)
Abstract
Background
Both carotid-femoral (cf) pulse wave velocity (PWV) and brachial-ankle (ba) PWV employ arterial sites that are not consistent with the path of blood flow. Few previous ...
Association of 25-hydroxyvitamin D deficiency with NT-pro BNP levels in patients with acute myocardial infarction: a cross-sectional analysis
(2011-12-15)
238 AMI patients from 21 U.S. centers to test the association of nutritional vitamin D (25-hydroxyvitamin D [25(OH)D]) deficiency with NT-proBNP levels. Levels of 25(OH)D levels were categorized as normal (≥30 ng/mL), insufficient (>20 - <...
Visual gene-network analysis reveals the cancer gene co-expression in human endometrial cancer
(2014-04-23)
Abstract
Background
Endometrial cancers (ECs) are the most common form of gynecologic malignancy. Recent studies have reported that ECs reveal distinct markers for molecular pathogenesis, which in turn is linked...
Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor
(2012-06-14)
β, IL-6, and NO levels, in response to inflammatory stimuli. This is the first report demonstrating that resveratrol and pterostilbene act as proteasome inhibitors, thus providing a mechanism for their anti-inflammatory effects....
Butyrylcholinesterase genotype and enzyme activity in relation to Gulf War illness: preliminary evidence of gene-exposure interaction from a case¿control study of 1991 Gulf War veterans
(2015-01-09)
Abstract
Background
Epidemiologic studies have implicated wartime exposures to acetylcholinesterase (AChE)-inhibiting chemicals as etiologic factors in Gulf War illness (GWI), the multisymptom ...
Factors influencing patient willingness to participate in genetic research after a myocardial infarction
(2011-06-15)
Abstract
Background
Achieving 'personalized medicine' requires enrolling representative cohorts into genetic studies, but patient self-selection may introduce bias. We sought to identify characteristics associated ...
Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data
(2011-01-25)
of quit attempts in the past year was 3.7 and 24.2% reported using pharmacotherapy in their most recent quit attempt. Motivation and confidence to quit were high.
Conclusion
KIS-III is the first study designed to examine both nicotine and bupropion...
delta-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens
(2011-02-28)
Abstract
Background
Chronic, low-grade inflammation provides a link between normal ageing and the pathogenesis of age-related diseases. A series of in vitro tests confirmed the strong anti-inflammatory activities ...
Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by delta-tocotrienol and quercetin.
(2011-12-20)
Abstract
Background
Changes in immune function believed to contribute to a variety of age-related diseases have been associated with increased production of nitric oxide (NO). We have recently reported that ...
Perceptions of neighborhood social environment and drug dependence among incarcerated women and men: a cross-sectional analysis
(2012-09-10)
Abstract
Background
Perception of neighborhood social environment can influence an individual’s susceptibility to drug dependence. However, this has never been examined with a jailed ...
RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritis
(2012-12-21)
the activation and proliferation of RASFs has been implicated in the pathogenesis of rheumatoid arthritis, further in-depth follow-up analysis of the transcriptional regulation reported in this study may shed light on molecular pathogenic mechanisms underlying...
Assessing responsiveness of generic and specific health related quality of life measures in heart failure
(2006-11-24)
Abstract
Background
Responsiveness, or sensitivity to clinical change, is an important consideration in selection of a ...
Assessing responsiveness of generic and specific health related quality of life measures in heart failure
(2006-11-24)
Abstract
Background
Responsiveness, or sensitivity to clinical change, is an important consideration in selection of a ...
Silencing of the IKKepsilon gene by siRNA inhibits invasiveness and growth of breast cancer cells
(2010-09-23)
Abstract
Introduction
IκB kinase ε (IKKε) is a member of the IKK family that plays an important role in the activation of NF-κB. Overexpressed in more than 30% of breast cancers, IKKε has been ...
A Bayesian Analysis for Identifying DNA Copy Number Variations Using a Compound Poisson Process
(2010-08-17)
To study chromosomal aberrations that may lead to cancer formation or genetic diseases, the array-based Comparative Genomic Hybridization (aCGH) technique is often used for detecting DNA copy number variants (CNVs). Various ...
Tandem repeat regions within the Burkholderia pseudomallei genome and their application for high resolution genotyping
(2007-03-30)
-locus VNTR analysis to examine 66 B. pseudomallei and 21 B. mallei isolates from around the world, as well as 95 lineages from a serial transfer experiment encompassing ~18,000 generations.
Results...
FEPI-MB: identifying SNPs-disease association using a Markov Blanket-based approach
(2011-11-24)
Abstract
Background
The interactions among genetic factors related to diseases are called epistasis. With the availability of ...