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The molecular underpinnings of neuronal cell identity in the stomatogastric ganglion of cancer borealis
(University of Missouri--Columbia, 2019)
of extensive molecular sequence knowledge in crustaceans. Here we generated de novo transcriptome assembly from central nervous system tissue for C. borealis producing 42,766 contigs, focusing on an initial identification, curation, and comparison of genes...
Applications of ancestry estimation in cattle population genetics
(University of Missouri--Columbia, 2019)
Accounting for ancestry and cryptic population structure is important in population genetic data analysis. The estimation of ancestry can help elucidate the effects of admixture or stratification on allele and genotype ...
Forest adaptation and transition in the eastern united states under climate change : a forest landscape modeling method
(University of Missouri--Columbia, 2018)
Forest management is rapidly shifting in focus to address the adaptive capacity of forests under uncertain future climates. Managers and researchers often utilize models to proactively develop strategies for forest adaptation ...
Living faith by seeking justice : practicing faith through activism in a faith and labor coalition
(University of Missouri--Columbia, 2010)
The combination of a critique of organized faith, along with an interest in pursuing faith expressions by living a particular sense of justice, leads some religious practitioners to discover new contexts to live out their ...
An exploratory and descriptive inquiry into the relationship between the goals of general education and disciplinary content in acting for non-majors courses in colleges and universities in the United States
(University of Missouri--Columbia, 2013)
A foundational requirement of undergraduate education in the United States is the completion of a general education curriculum. One goal of general education is to introduce students to habits of mind leading to the ...
Novel chemical mechanisms of DNA damage by natural products
(University of Missouri--Columbia, 2007)
that the molecule is very toxic to human pancreatic carcinoma cell line (MiaPaCa) and fragments DNA extensively with an IC[subscript 50] of 50 nM. The elucidation of molecular mechanism behind the rapid depurination event might help to understand more about...
Differential gene and protein expression in pig nuclear transfer extraembryonic membranes and blastocyst stage embryos
(University of Missouri--Columbia, 2010)
Nuclear transfer (cloning) is the process of transferring a donor cell nucleus into an enucleated oocyte. The oocyte and donor cell are subsequently fused and activated to allow for nuclear reprogramming and continued ...
Characterization of SF-hERR[beta] repression of human estrogen receptor alpha and estrogen receptor-beta transcriptional activities
(University of Missouri--Columbia, 2009)
Discovery of new ways to modulate estrogen actions through estrogen receptor is always exciting because of the importance of estrogen and ERs in many human diseases. In this dissertation, we report our discovery of the ...
In vitro characterization of Nudt16 orthologs by sequence and function provide evidence supporting a nuclear RNA degradation pathway
(University of Missouri--Columbia, 2009)
Nudt16, previously called X29, is known to be a metal-dependent decapping enzyme expressed in mammals and Xenopus . Nudt16 has been proposed to be the catalytic component of a previously unknown nuclear RNA degradation ...
Understanding the impact of MSHSAA by-law 3.15.3 on participation in Missouri high school athletics from 2008-2016
(University of Missouri--Columbia, 2019)
This quantitative policy analysis seeks to understand the potential impact of MSHSAA By-Law, 3.15.3, the contact day policy, on sport participation in Missouri high school athletics. This policy increased the number of ...
Bumping up the body : examining the impact of celebrity gossip magazines on body image during pregnancy
(University of Missouri--Columbia, 2010)
The present analysis examined the impact of celebrity gossip magazine coverage on pregnant women through both quantitative and qualitative methods. Study 1 employed both objectification theory (Fredrickson & Roberts, 1997) ...
Synthesis and evaluation of 105Rhodium(III) complexes derived from diaminodithioether (DADTE) ligands
(University of Missouri--Columbia, 2006)
Seven analogoues of tetradentate acyclic diaminodithioether (DADTE)ligands were synthesized and characterized. R₂SC(R₁)₂)CHnN(CH₂)mNCHn((R₁)₂C)SR₂ 222-gdm (L3): m = 1, n = 1, R₁ = -CH₃ and R₂ = -H; 222-gdm-pmBz (L4): m = ...
Woke : internet news and social media on recent attitudes towards police use of force
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] News media has long featured high-profile incidents of police use of force; however, exposure to these incidents may be increasing because of the ...
Synthesis and photochemistry of PT (IV) hydroxo complexes
(University of Missouri--Columbia, 2015)
Global energy consumption and the production of clean renewable energy have become greater challenges. Sunlight-induced splitting of water into H2 and O2 is one of the leading strategies to achieve clean and renewable ...
This great prayerful tradition : American presidents preaching public theology at the National Prayer Breakfast
(University of Missouri--Columbia, 2018)
This study presents a comprehensive analysis of the speeches delivered by American presidents at the National Prayer Breakfast (NPB) from its inception in 1953 until 2016, as well as the rhetorical context of the NPB. ...
Molecular mechanisms of tumor invasion in three-dimensional collagen matrices
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Cancer remains a significant cause of morbidity and mortality worldwide, and invasion and metastasis substantially contribute to poor prognosis and ...
Topical Nanoparticulate Formulation of Drugs for Ocular Keratitis
(2015-08-11)
The primary objective of this project is to develop drug-loaded polymeric nanoparticles
suspended in a biocompatible gel for topical delivery of therapeutic agents commonly
employed in the treatment of ocular viral/bacterial ...
Developmental programming by xenoestrogens
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Xenoestrogens (XE) are chemicals in the environment that mimic the body's natural steroidal estrogens. Developmental exposure to XE may interfere with ...
Hydrology, vegetation and waterbird response to land management strategies in the San Luis Valley
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The distribution of wetlands in the San Luis Valley has been altered by human modifications that influence the timing, distribution and characteristics ...
Unraveling the role of the endogenous complex gut microbiota in the Pirc rat model of human colon cancer
(University of Missouri--Columbia, 2018)
The gut microbiota (GM) has recently been shown to modulate several systemic conditions in human and model systems, most importantly in intestinal disorders. It has also been demonstrated to have significant impacts on ...