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Now showing items 41-60 of 120
Regulation of L-type calcium channel sparklet activity by PKC and C-src
(University of Missouri--Columbia, 2010)
Ca2+ sparklets are elementary fluorescence events associated with Ca2+ entry through L-type Ca2+ channels (Cav1.2) channels and are classified as persistent and low activity Ca2+ sparklets. Persistent Ca2+ sparklets are ...
A modeling approach to ultrasound evaluation of material properties
(University of Missouri--Columbia, 2010)
A method for estimating the mechanical properties of a viscoelastic sample from ultrasound measurements was developed. The sample was represented as a mechanical network according to the Kelvin-Voigt model and linear ...
True depth resolved polarization sensitive optical coherence tomography
(University of Missouri--Columbia, 2012)
Polarization sensitive optical coherence tomography (PSOCT) can image sample polarization properties including retardance, diattenuance, and optical axis and has potential applications in many biomedical fields. However, ...
H₂O₂-mediated RAGE up-regulation on A[beta]-induced superoxide in cerebral endothelial cells
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The up-regulation of receptor for advanced glycation (RAGE) product has been implicated in the pathophysiology of Alzheimer's disease (AD). Elevated ...
The use of supercritical fluids to process biomass for fuel
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Soybean flakes were extracted using supercritical carbon dioxide at 48.3 MPa and 80 °C, which is a higher temperature than previously reported. Several ...
Gold nanoparticle mediated membrane permeabilization of phytochemical into breast cancer cells
(University of Missouri--Columbia, 2014)
Supercritical water gasification of waste residues
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] A batch reactor was built in the University of Missouri Carbon Recycling Center to explore the thermo-chemical conversion of motor oil as a model ...
Study of low noise high throughput microchip device for electrochemical measurement from single cells
(University of Missouri--Columbia, 2012)
We are developing transparent multi- electrochemical electrode arrays on microchips in order to automate measurement of quantal exocytosis of oxidizable transmitter from individual vesicles. In order to achieve low noise ...
Characterization [of] nucleic acids unwinding and exploring its application in miRNA detection in the nanopore
(University of Missouri--Columbia, 2012)
MicroRNAs (miRNAs) are a class of short (~14-27 nucleotides) noncoding RNAs that regulate gene expression at the post-transcriptional level. Aberrant expression of miRNAs has been found in all types of tumors. Reverse ...
Efficacy of nanoparticles in achieving hemostasis
(University of Missouri--Columbia, 2012)
Uncontrollable hemorrhage is significant cause of preventable death in the military and civilian setting. Hemostatic wound dressings have been created in an attempt to rectify this problem, but none currently on the market ...
Biophysical and photobiological modulations of cellular pathways in Alzheimer's disease
(University of Missouri--Columbia, 2010)
The overall goal of this thesis work is to study the effects of biomodulations on Alzheimer's disease (AD) related cellular pathways, using biophysical and photobiological methods, including secretory phospholipase A2, ...
Predicting switchgrass biomass and ethanol potential on claypan soil landscapes
(University of Missouri--Columbia, 2015)
Switchgrass (Panicum virgatum L.) yield on claypan soils was evaluated with a crop growth model and for actual ethanol production potential. Specifically, Agricultural Land Management Alternatives with Numerical Assessment ...
Concurrent simulation of a subject specific musculoskeletal model with anatomical knee
(University of Missouri--Columbia, 2015)
Computational models of the knee provide us with a better understanding of ligament and joint contact forces during ambulatory activities. Thus, such models can be used to devise better injury prevention methods, as well ...
Atomic force microscopy (AFM) for measurement of cell elastic properties
(University of Missouri--Columbia, 2015)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This thesis presents data on the use of atomic force microscopy (AFM) for manipulating, detecting, and resolving the mechanical characteristics of ...
Study of dielectrophoresis effect of dipolar molecules in electric field of nanopore and development of medical diagnostic nanopore sensor
(University of Missouri--Columbia, 2015)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The nanopore sensor can detect cancer-derived nucleic acid biomarkers such as microRNAs (miRNAs), providing a noninvasive tool potentially useful in ...
Rapid estimation of antibiotic efficacy of low bacterial inoculums using multi-frequency impedance measurements
(University of Missouri--Columbia, 2015)
Background: In order to obtain Minimum Inhibitory Concentrations (MICs), antibiotics are, by convention, tested against turbidometrically standard suspensions containing [about]5x105 CFU/ml of bacteria. This not only fails ...
Integration of single-cell electropermeabilization together with electrochemical measurement of quantal exocytosis on microchips
(University of Missouri--Columbia, 2013)
An electrochemical microelectrode located immediately adjacent to a single neuroendocrine cell can record spikes of amperometric current that result from quantal exocytosis of oxidizable transmitter from individual vesicles. ...
Soil property estimation using visible and near-infrared reflectance
(University of Missouri--Columbia, 2012)
Site-specific management of crop production systems holds promise for maintaining high yields while preserving soil quality. This management requires detailed spatial data on soil physical and chemical characteristics but ...
Electrospinning collagen and hyaluronic acid nanofiber meshes
(University of Missouri--Columbia, 2011)
Osteoporosis is a worldwide burden affecting over 200 million people. There are many risk factors associated with osteoporosis, but they all lead to decreased bone strength and an increased chance of bone fracture. The ...
Polyurethane foams made from bio-based polyols
(University of Missouri--Columbia, 2011)
Polyurethane (PU) foams have great applications in industry. The raw materials of PU, polyol and isocyanate, are conventionally derived from petroleum. Bio-based polyols are promising substitutes for petrochemical polyols ...