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Now showing items 6801-6820 of 6905
Development of Protein Based PCBP2 siRNA Nanocomplex for Liver Fibrosis Therapy
(University of Missouri -- Kansas City, 2018)
The objective of this dissertation is to develop a protein-based siRNA
nanocomplex for the treatment of alcoholic liver fibrosis. Our laboratory recently
discovered that silencing the poly (rC) binding protein 2 (PCBP2) ...
The use of pluripotent stem cells as a model for early human placentation
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Throughout gestation, the placenta plays a critical role in ensuring proper development of the fetus. The placenta functions to exchange nutrients, ...
"This land is my land" : authority and landscape in American women's nonfiction, 1843-1903
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] "Thus, the arc of my dissertation—from a landscape that is local and familiar to one that is vast and often incomprehensible—suggests that women confront ...
Non-emergency exits : voluntary retirements from legislatures
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Retirement is the main source of legislative turnover in the United States Congress. The incumbency advantage in congressional elections is so strong ...
Analysis and design of reinforced concrete wall systems for blast
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Building envelope is the first and most critical line of defense for a structure against external explosion. Building envelope can be divided into two ...
Digestible amino acid requirements for young female turkeys
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Nine experiments were conducted to determine the optimal digestible isoleucine (dIle), valine (dVal), leucine (dLeu), phenylalanine plus tyrosine (dPT) ...
Studying and developing the thin film membranes for reverse osmosis application
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Desalination by semi-permeable membranes is the most applicable method of water-salt separation, where reverse osmosis (RO) account for the major portion ...
Emergent properties in the artificial magnetic honeycomb lattice of ultra-small elements
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The artificial magnetic honeycomb lattice is expected to manifest a broad and tunable range of novel magnetic phenomena associated with the geometric ...
Dynamically-scalable distributed cluster and cloud computing framework for IoT media data
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The Internet of Things (IoT) continues to expand; as daily new smart-devices are connected to Internet and adding to a deluge of data created by our ...
Preparing birds to fly : Lloyd Richards and the actor
(University of Missouri--Columbia, 2013)
Lloyd Richards (1919-2006) was one of the preeminent theatre practitioners in the United States from the mid-twentieth century through the beginning of the twenty-first. Through his work as Artistic Director of the Eugene ...
Peptide-Based Platform For Cancer Therapeutics And Drug Transportation Across Blood-Brain Barrier
(University of Missouri -- Kansas City, 2018)
Prostate cancer is the most common male malignancy and remains the second-leading
cause of death due to cancer in American men. While surgery and radiation are effective in
prostate cancer therapy at early stages, the ...
Pretargeted cancer radioimmunotherapy and radioimaging using antibodies and antibody fragments
(University of Missouri--Columbia, 2018)
Over the last few decades, antibodies have become the mainstay of cancer diagnosis and therapeutics. In traditional radioimmunotherapy (RIT), tumor targeting antibodies are directly conjugated with radioisotopes and depending ...
Investigation of methods and factors influencing mouse oocyte quality, in vitro fertilization and embryo development
(University of Missouri--Columbia, 2018)
Mice are one of the most commonly used rodent species as a model for biomedical research to better understand molecular, genetic, and cellular causes of human disease and disorders. The production of good quality oocytes ...
KOLAM : human computer interfaces fro visual analytics in big data imagery
(University of Missouri--Columbia, 2018)
In the present day, we are faced with a deluge of disparate and dynamic information from multiple heterogeneous sources. Among these are the big data imagery datasets that are rapidly being generated via mature acquisition ...
Engineering of Human Acid Phosphatase Enzyme Sensitive Nanomedicine for HIV/AIDS Prevention by Topical Route
(University of Missouri -- Kansas City, 2018)
This study is divided into two aims. Aim #1 focuses on the development and
characterization of tenofovir (TFV) loaded a stimuli sensitive nanomedicine against male to
female HIV/AIDS infection. Aim #2 focus on the ...
Regression analysis of longitudinal covariates with censored and longitudinal outcome
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Longitudinal data contain repeated measurements of variables on the same experimental subject. It is often of interest to analyze the relationship ...
The Evaluation of Permeable Cementitious Media for Nutrient Removal
(University of Missouri -- Kansas City, 2017)
Excessive amounts of nutrients in surface and ground waters can interfere with the
quality of aquatic and human life. Permeable pavement systems have been studied for
contaminant removal, but there are limitations to ...
Hand Gesture Recognition via Electromyographic (EMG) Armband for CAD Software CONTROL
(University of Missouri -- Kansas City, 2018)
In the past, computers - whether personal or at work - required a mouse and key
board to interact with them, and they are still used to this day. Even for video games a
physical tool (controller) is needed to interact ...
Climate and land use effects on hydrologic processes and water allocation in a primarily rain-fed, agricultural watershed
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] There is a need to raise our understanding of the impact of climate variability and change on hydrologic processes at the watershed scale. This is ...
Assessing the effects of anticoagulant rodenticides on non-target fish species
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Invasive rat species have negatively affected island ecosystems contributing to the decline and extinction of many endemic species. The eradication of ...