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Nutritional intervention in the early growing broiler chick
(University of Missouri--Columbia, 2016)
As the broiler chicken continues to grow faster and larger, the time to slaughter continually decreases. Broilers are commonly slaughtered at 5-8 weeks of age and so the post-hatch period has become a larger and more ...
Developmental exposure to bisphenol a (BPA) and ethinyl estradiol (EE) and effects on F1 parental care and F2 pup parameters in California mice (Peromyscus californicus)
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Environmental exposure during the perinatal period can promote health and disease in offspring, otherwise coined developmental origins of health and ...
Transgenerational effects of in utero heat stress on reproduction in pigs
(University of Missouri--Columbia, 2017)
Seasonal infertility caused by high ambient temperatures and humidity during the summer months can have negative effects on the reproduction of female swine. These conditions may cause heat stress leading to large economic ...
Gold nanoclusters and fluorescence-based sensing
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The main topic of this dissertation focuses on development of analytical methods, mainly modification and application of metal nanoclusters in ...
Ruminal degradation of protein and carbohydrate using a batch culture system, and response to roughage removal, rumen modifier inclusion and postruminal amino acid supply in feedlot cattle
(University of Missouri--Columbia, 2017)
Three main studies were conducted to characterize protein and carbohydrate ruminal degradation using a batch culture system, demonstrate and responses to roughage removal, rumen modifiers inclusion and postruminal amino ...
Ablation of conceptus PTGS2 provides a new understanding of early pregnancy events in the pig
(University of Missouri--Columbia, 2019)
Pig conceptuses produce and secrete estrogens (E[2]), interleukin 1 beta 2 (IL1B2), and prostaglandins (PGs) during the period of rapid trophoblast elongation and establishment of pregnancy. Previous studies established ...
Reduced autophagy contributes to inefficient DNA damage repair in mouse oocytes
(University of Missouri--Columbia, 2022)
The DNA damage is a major problem that, in somatic cells, leads to mutagenesis and premature aging. However, this is not the case in fully differentiated germ cells. Why DNA damage repair (DDR) machinery is not robust in ...
Investigating the role of a lncRNA (4833427F10Rik) in mouse placental development and function
(University of Missouri--Columbia, 2022)
Long non-coding RNAs (lncRNAs) have traditionally been viewed as transcriptional noise. However, experimental evidence of their cell-type-specific expression, presence of functional genetic elements, along with their role ...
Glutamine metabolism and interactions with mechanistic target of rapamycin complex 1 in porcine preimplantation embryos
(University of Missouri--Columbia, 2021)
The ability to culture embryos has created opportunities for animal agriculture, including the refined selection of superior genetics, and for the medical field, allowing couples experiencing infertility to have biological ...
Characterization of the genetic landscape of feline oral squamous cell carcinoma
(University of Missouri--Columbia, 2022)
Over 94 million domestic cats are susceptible to cancers and other common and rare diseases. While cancer treatment in cats increasingly mirrors that available in humans, treatment failures are more frequent. There are no ...
Taxonomic and metagenomic approaches to diet, health, and breeds of ruminants
(University of Missouri--Columbia, 2020)
Ruminant mammals maintain a symbiotic relationship with their gut microbiome, the organisms of which break complex plant matter into metabolites that are absorbed by the host animal for its nutrition. Building on prior ...
Regulation of fetal brain development in short versus long lived mice
(University of Missouri--Columbia, 2022)
How fetal brain development is regulated in mice with reduced life span is a primary objective of this research. Three studies were performed to investigate the fetal brain development in short and lived mice strains. The ...
Using metabolic and biochemical characteristics of postmortem muscle to investigate the interconnectedness of beef color, flavor, and tenderness
(University of Missouri--Columbia, 2021)
Understanding relationships between beef palatability and quality components are crucial for continued production of high quality and consistent beef products. Myoglobin concentrations at 48 and 336 h resulted in moderate, ...
Systemic effects of mastitis in the dairy cow : identifying mechanisms underlying impaired lactation in non-inflamed glands
(University of Missouri--Columbia, 2020)
Efficient milk production is temporarily compromised during the inflammatory response to lipopolysaccharide (LPS). Generally, the most severe losses are localized to individual mammary glands with overt cases of mastitis. ...
Improved cloning efficiency by chemically induced metabolic reprogramming of donor cells used for porcine somatic cell nuclear transfer
(University of Missouri--Columbia, 2019)
The use of somatic cell nuclear transfer (SCNT) to create agricultural and biomedical models is extremely useful for understanding how we can improve the efficiency of production agriculture, as well as how we can better ...
Extracellular vesicles, lipids, and lipoproteins in early pregnant sheep
(University of Missouri--Columbia, 2021)
In sheep, pregnancy establishment encompasses conceptus elongation, implantation, and placentation. These events are regulated by factors present within the uterine luminal fluid (ULF) from the endometrial epithelium and ...
Conceptus interferon gamma is essential for pregnancy maintenance in the pig
(University of Missouri--Columbia, 2021)
Establishment and maintenance of pregnancy in the pig is a complex process that relies on adequate communication between the conceptus and maternal uterine endometrium. During the peri-implantation period, the conceptuses ...
Investigation of methods and factors influencing mouse oocyte quality, in vitro fertilization and embryo development
(University of Missouri--Columbia, 2018)
Mice are one of the most commonly used rodent species as a model for biomedical research to better understand molecular, genetic, and cellular causes of human disease and disorders. The production of good quality oocytes ...
Paternal effects on pre-implantation embryo development in cattle
(University of Missouri--Columbia, 2021)
Currently, sire fertility is measured using sire conception rate (SCR), which is not always indicative of embryo development. Since the majority of pregnancy loss in dairy cattle occurs during the early embryonic period, ...
Evaluation of the 7 and 7 synch protocol for control of the estrous cycle among beef cows prior to fixed-time artificial insemination with sex-sorted or conventional semen
(University of Missouri--Columbia, 2021)
Experiment 1 was conducted to compare 7 and 7 Synch and the 7-day CO-Synch + controlled internal drug release (CIDR[copyright]) protocols prior to fixed-time artificial insemination (FTAI) of beef cows with conventional ...