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Now showing items 61-80 of 124
Effects of diet and exercise on carotid lesions in male pigs
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
The objective of this study was to examine the influence of aerobic exercise-training on atherosclerotic lesion appearance and composition in the carotid artery of male, miniature Yucatan pigs fed a high-fat, high-cholesterol ...
Oxidative stress alters cell morphology and cell death indices in immortalized astrocytes
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Menadione, usually known as vitamin K3, also serves as a trigger for oxidative stress, delivering reactive oxygen species (ROS) upon entering the cells. Astrocytes are glial cells that are found in the brain and are extremely ...
Functional analysis of MPK3 and MPK6, two mitogen-activated protine kinases in Arabidopsis thaliana
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Mitogen-activated protein kinase (MAPK) cascades are major pathways involved in the transduction of extracellular signals into intracellular responses. A MAPK cascade consists of three kinases; MAPK, MAPK kinase (MAPKK or ...
Characterization of degeneration in the retina, brain and spinal cord of the Cln1 knockout mouse
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
The neuronal-ceroid lipofuscinoses (NCLs; often referred to as Battens Disease) are a group of hereditary disorders of childhood. Symptoms of NCLs are characterized by neurodegeneration with progressive neural cell death ...
Modeling firing patterns of medium spiny neurons
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
The alternation in firing patterns of medium spiny neurons of the Nucleus Accumbens , a key structure in the brain's reward pathway, due to chronic and acute cocaine use was investigated through change of ion channel and ...
Use of antisense oligonucleotides to enhance exon 7 incorporation in the pre-mRNA splicing of SMN2
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Spinal muscular atrophy (SMA) is a neurodegenerative disorder that is relatively common in humans and is caused by loss of the survival motor neuron 1 (SMN1) gene. SMA is the leading cause of hereditary infant mortality ...
Mathematical modeling of obsessive compulsive disorder
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
We all at some point become fixated with certain actions or ideas. However, for the two to three percent of the world population with obsessive compulsive disorder (OCD), these fixations become so intense that the individual ...
Neutron activation analysis of mercury in petroleum distillates
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
In liquefied natural gas (LNG) plants and nitrogen rejections units (NRU) that utilize aluminum heat exchangers, mercury (Hg) contaminates can result in corrosion of equipment, poisoning of catalysts, mechanical failure, ...
Production of nano particles
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Nano particles (particles having diameters in the nanometer range) have applications in a variety of areas including medical, environmental, sensor, to name a few. However, the production of nano particles having uniform ...
The role of the cytoskeleton in the formation and properties of membrane tethers
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Membrane tethers play a critical role in cell adhesion and cell motility. This can be observed in the arrest of neutrophils on the endothelial wall of blood vessels during inflammatory response. Tethers are employed to ...
Phosphorylation of EGFR, ERK 1/2 and downstream transcription factors after P2Y2 receptor activation in a human submandibular gland cell line
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
P2 nucleotide receptors mediate a variety of biological responses and are activated by the extracellular nucleotides adenosine triphosphate (ATP), adenosine diphosphate (ADP), uridine triphosphate (UTP), uridine diphosphate ...
Genotypic analysis of receptor-like protein kinases with leucine-rich repeat motifs
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Receptor-like protein kinases (RLKs) are transmembrane proteins that transmit extracellular signals across a membrane with the use of an intracellular kinase domain. RLKs play important roles in plant growth and development, ...
Genotype and phenotype of Nicotiana alata x Nicotina rastroensis
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Gametophytic self-incompability (SI) is a process which enables plants to prevent inbreeding depression by rejecting self-pollen and pollen from closely related individuals. S-specific pollen rejection is controlled on a ...
Exploring the possibility of new ERR isoforms in primates and humans
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
It is well known that estrogen is a risk factor for breast cancer. Hence, understanding the relationship between estrogen and breast cancer is significant for physiological and disease related pathways. Traditional thought ...
Membrane tether formation studied with magnetic tweezers
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Membrane tethers are ubiquitous nanometer-diameter cylindrical extensions of biological membranes. They form through either active or passive processes, by locally acting tensional forces. The physical properties of membrane ...
Adaptive controls and anesthesiology: Is there a future?
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
During a patient's surgery, an anesthesiologist has to periodically adjust controls on drug-delivery machines to keep a patient's consciousness at a desired level (a BIS value between 40 and 60). If this physician did not ...
Synthesis and stability of rhenium tricarbonyl radiotracers
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Metal tricarbonyl complexes can be employed for cancer diagnosis and therapy using the radioisotopes Tc-99m or Re-188. These radiopharmaceuticals can be designed with specific physical and biological qualities such as low ...
Developments of a pid temperature control system for a PCR chip
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
A Polymerase Chain Reaction on chip needs a precise temperature control for the reaction cycle. It is necessary to create and develop a good temperature control system for the operation of the PCR chip. Thin Pt film will ...
Examination of the robustness of viscosity sensitive molecular rotors against chemical modification
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Molecular rotors, a special class of compounds which form twisted intramolecular charge transfer complexes (TICT), have dual deexcitation processes - intramolecular rotation and fluorescence emission. Molecular rotors ...
Going for a triple play: Making a GLH-1; GLH -4; KGB-1 triple mutant
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Essential to the germline determination of the nematode Caenorhabditis elegans are RNA-protein complexes found in germ cell cytoplasms known as P granules. Germline RNA helicase (GLH) proteins are components of P granules ...