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Now showing items 61-80 of 381
What is the interval for monitoring warfarin therapy once therapeutic levels are achieved?
(Family Physicians Inquiries Network, 2005)
The international normalized ratio (INR) should be measured monthly once therapeutic levels are achieved and are stable for at least 8 weeks, although treatment should be individualized and an increased frequency may be ...
For those intolerant to ACE inhibitors and ARBs, what is the best therapy for reducing the risk of diabetic nephropathy?
(Family Physicians Inquiries Network, 2005)
Angiotensin-converting enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) are the first-line agents for reducing the risk of diabetic nephropathy. For patients intolerant to these agents, non-dihydropyridine ...
What are the relative risks and benefits of progestin-only contraceptives?
(Family Physicians Inquiries Network, 2005)
Little evidence describes the risks and benefits of progestin-only contraceptives therapy. No good-quality evidence exists to determine the risk of cancer associated with progestin-only contraceptives. Data are insufficient ...
What is the recommended evaluation and treatment for elevated serum prolactin?
(Family Physicians Inquiries Network, 2005)
History and physical examination can distinguish among most physiologic, pharmacologic, or pathologic causes of an elevated serum prolactin level (SPL) (strength of recommendation [SOR]: C, expert opinion). Patients with ...
Which late-stage Alzheimer's patients should be referred for hospice care?
(Family Physicians Inquiries Network, 2005)
Medicare guidelines are used to determine eligibility for hospice care (strength of recommendation [SOR]: C, based on expert opinion), but they correlate with 6-month mortality no better than an experienced clinician's ...
Who should get hepatitis A vaccination?
(Family Physicians Inquiries Network, 2005)
The following groups are at increased risk of contracting or having severe outcomes from hepatitis A and should receive vaccination.Persons traveling to or working in countries that have high or intermediate rates of ...
What is the addiction risk associated with tramadol?
(Family Physicians Inquiries Network, 2005)
Tramadol (Ultram, generic and with acetaminophen in Ultracet) carries a risk of substance abuse (strength of recommendation [SOR]: B, based on case report surveillance programs). While it appears that tramadol's risk of ...
Is therapy based on endoscopy results better than empiric therapy for dyspepsia?
(Family Physicians Inquiries Network, 2005)
In the initial management of dyspepsia for patients without "alarm" symptoms (weight loss, recurrent vomiting, dysphagia, anemia, evidence of bleeding, onset of dyspepsia after age 45 years), therapy based on the results ...
Can type 2 diabetes be prevented through diet and exercise?
(Family Physicians Inquiries Network, 2005)
Diets that result in long-term weight loss of 5% to 7%, along with moderate-intensity exercise for more than 150 minutes per week, reduce the incidence of type 2 diabetes for patients with impaired glucose tolerance (IGT) ...
What is the best regimen for newly diagnosed hypertension?
(Family Physicians Inquiries Network, 2005)
Low-dose thiazide diuretics (eg, hydrochlorothiazide 12.5 to 25 mg/d) are the best first-line pharmacotherapy for treating uncomplicated hypertension(strength of recommendation [SOR]: A, based on randomized trials [RCTs] ...
What is angular cheilitis and how is it treated?
(Family Physicians Inquiries Network, 2005)
Cheilitis is a broad term that describes inflammation of the lip surface characterized by dry scaling and fissuring. Specific types are atopic, angular, granulomatous, and actinic. Angular cheilitis is commonly seen in ...
Do statins delay onset or slow progression of Alzheimer's dementia?
(Family Physicians Inquiries Network, 2005)
Statins (coenzyme-A reductase inhibitors) should not be used with the single intent to delay the onset or slow the progression of dementia. Large randomized control trials (RCTs) found that the administration of a statin ...
Do antibiotics interfere with the efficacy of oral contraceptives?
(Family Physicians Inquiries Network, 2005)
Among antibiotics, only rifampin has been demonstrated to interfere with the effectiveness of oral contraceptives (OCs) (strength of recommendation [SOR]: C, limited case series). There is little convincing evidence to ...
How long is expectant management safe in first-trimester miscarriage?
(Family Physicians Inquiries Network, 2005)
More than 80% of women with a first-trimester spontaneous abortion have complete natural passage of tissue within 2 to 6 weeks with no higher complication rate than that from surgical intervention (strength of recommendation ...
Sleep apnea in adults: How accurate is clinical prediction?
(Family Physicians Inquiries Network, 2009)
Questionnaires, physical examination, and clinical prediction rules estimate the pretest probability of obstructive sleep apnea hypopnea syndrome (OSAHS), but are not specific enough to make the diagnosis (strength of recommendation [SOR]: B, meta...
What is the best treatment for analgesic rebound headaches?
(Family Physicians Inquiries Network, 2005)
Abrupt discontinuation of the offending analgesic(s), and treating rebound headaches with dihydroergotamine (DHE) as needed, results in significant improvement for most patients (strength of recommendation [SOR]: C; based ...
How should we follow athletes after a concussion?
(Family Physicians Inquiries Network, 2005)
Athletes sustaining a concussion should be held from contact activities a minimum of 7 days; they must be asymptomatic and their coordination and neuropsychological tests should have returned to their pre-injury baseline ...
How does colonoscopy compare with fecal occult blood testing as a screening tool for colon cancer?
(Family Physicians Inquiries Network, 2005)
No studies have directly compared colonoscopy with fecal occult blood testing (FOBT). Multiple screening trials have demonstrated that a primary strategy of 3-card home FOBT with follow-up colonoscopy for positive results ...
Do group visits improve HbA1c more than individual visits in patients with T2DM?
(Family Physicians Inquiries Network, 2005)
) by 0.3% to 0.9% over usual care (strength of recommendation [SOR]: B, meta-analyses of randomized clinical trials [RCTs] with moderate to high risk of bias). Patients taking oral antidiabetic agents alone appear to benefit more than patients on insulin...
What is the best treatment for nocturnal enuresis in children?
(Family Physicians Inquiries Network, 2005)
For children with primary nocturnal enuresis,
treatment with enuresis alarms reduced the
number of wet nights by almost 4 per week, with almost half of patients remaining dry for 3 months after treatment (strength of ...