Search
Now showing items 61-78 of 78
Computational analysis and predictive modeling of polymorph descriptors
(2013-02-04)
Abstract
Background
A computation approach based on integrating high throughput binding affinity comparison and binding descriptor classifications was utilized to establish the ...
The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line
(2009-12-10)
Abstract
Background
N-acylethanolamines (NAEs) are lipids upregulated in response to cell and tissue injury and are involved ...
The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line
(2009-12-10)
Abstract
Background
N-acylethanolamines (NAEs) are lipids upregulated in response to cell and tissue injury and are involved ...
ART adherence changes among patients in community substance use treatment: a preliminary analysis from MACH14
(2012-10-11)
Abstract
Background
Opiate substitution treatment has been associated with better adherence to lifesaving antiretroviral medications, but the impact of other substance abuse treatment on ...
An embedded multichannel telemetry unit for bone strain monitoring
(2013-10-17)
Abstract
An embedded telemetry unit for bone strain monitoring is presented. The telemetry unit is designed using commercially available components to lower design time and manufacturing ...
One-year health status outcomes of unstable angina versus myocardial infarction: a prospective, observational cohort study of ACS survivors
(2007-09-12)
Abstract
Background
Unstable angina (UA) patients have lower mortality and reinfarction risks than ST-elevation (STEMI) or non-ST elevation myocardial infarction (NSTEMI) patients ...
One-year health status outcomes of unstable angina versus myocardial infarction: a prospective, observational cohort study of ACS survivors
(2007-09-12)
Abstract
Background
Unstable angina (UA) patients have lower mortality and reinfarction risks than ST-elevation (STEMI) or non-ST elevation myocardial infarction (NSTEMI) patients ...
HAPSIMU: a genetic simulation platform for population-based association studies
(2008-08-05)
Abstract
Background
Population structure is an important cause leading to inconsistent results in population-based association ...
HAPSIMU: a genetic simulation platform for population-based association studies
(2008-08-05)
Abstract
Background
Population structure is an important cause leading to inconsistent results in population-based association ...
Involvement of metabotropic glutamate receptor 5, AKT/PI3K Signaling and NF-kappaB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes
(2012-03-15)
Abstract
Methamphetamine (MA) is one of the commonly used illicit drugs and the central nervous system toxicity of MA is well documented. The mechanisms contributing to this toxicity have not been fully elucidated. In this ...
Human immunodeficiency virus type 1 viral protein R (Vpr) induces CCL5 expression in astrocytes via PI3K and MAPK signaling pathways
(2013-11-13)
Abstract
Background
Neurocognitive impairments remain prevalent in HIV-1 infected individuals despite current antiretroviral therapies. It is increasingly becoming evident that astrocytes ...
Cardiac thromboxane A2 receptor activation does not directly induce cardiomyocyte hypertrophy but does cause cell death that is prevented with gentamicin and 2-APB
(2014-12-17)
Abstract
Background
We have previously shown that the thromboxane (TXA2) receptor agonist, U46619, can directly induce ventricular arrhythmias that were associated with increases in intracellular ...
The role of Candida albicans homologous recombination factors Rad54 and Rdh54 in DNA damage sensitivity
(2011-09-27)
Abstract
Background
The fungal pathogen Candida albicans is frequently seen in immune suppressed patients, and resistance to one of the most widely used antifungals, fluconazole (FLC), can evolve rapidly. In recent years ...
Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental models
(2011-10-12)
Abstract
Background
Inflammation has been implicated in a variety of diseases associated with ageing, including cancer, cardiovascular, and neurologic diseases. We have recently established that the proteasome ...
A unified phylogeny-based nomenclature for histone variants
(2012-05-31)
AbstractHistone variants are non-allelic protein isoforms that play key roles in diversifying chromatin structure. The known number of such variants has greatly increased in recent years, but the lack of naming conventions ...
The impact of diabetes on one-year health status outcomes following acute coronary syndromes
(2006-10-24)
Abstract
Background
Diabetes is an important predictor of mortality patients with ACS. However, little is known about the ...
The impact of diabetes on one-year health status outcomes following acute coronary syndromes
(2006-10-24)
Abstract
Background
Diabetes is an important predictor of mortality patients with ACS. However, little is known about the ...
GAL1-SceI directed site-specific genomic (gsSSG) mutagenesis: a method for precisely targeting point mutations in S. cerevisiae.
(2011-12-05)
Abstract
Background
Precise targeted mutations are defined as targeted mutations that do not require the retention of other genetic changes, such as marker genes, near the mutation site. In the yeast, S. cerevisiae, ...