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What are the best prophylactic drugs for migraine?
(Family Physicians Inquiries Network, 2009)
Beta-blockers without intrinsic sympathomimetic activity, amitriptyline, divalproex sodium/sodium valproate, and topiramate are the most effective drugs for preventing episodic migraine (strength of recommendation: A, ...
What treatment works best for tennis elbow?
(Family Physicians Inquiries Network, 2009)
Topical or oral nonsteroidal anti- inflammatory medications (NSAIDs), corticosteroid injection, and acupuncture are more helpful than placebo in treating lateral epicondylitis, or tennis elbow (strength of recommendation ...
Statin Therapy in Patients with Type 2 Diabetes
(Family Physicians Inquiries Network, 2005)
Based on current evidence, statin therapy should be offered to all patients with type 2 diabetes who are known to have coronary artery disease. [Strength of recommendation: A] For patients older than 40 years with type 2 ...
What does the evidence tell us about treating very-high-risk patients to an LDL <70 mg/dL?
(Family Physicians Inquiries Network, 2009)
No studies directly compare low-density lipoprotein (LDL) levels <70 mg/dL to levels of 71 to 100 mg/dL in very-high-risk patients. However, no evidence suggests a "floor" for LDL cholesterol levels beyond which further ...
Aspirin in Patients with Acute Ischemic Stroke
(Family Physicians Inquiries Network, 2009)
Aspirin in a daily dose of 160 to 300 mg initiated within 48 hours of symptom onset results in a net decrease in morbidity and mortality caused by acute ischemic stroke (Strength of Recommendation [SOR]: A, based on a ...
What's the best way to monitor low-risk patients with a history of differentiated thyroid cancer?
(Family Physicians Inquiries Network, 2009)
Recombinant human thyrotropin (rhTSH)-stimulated serum thyroglobulin (Tg) level alone is sufficient to monitor for recurrent disease in low-risk patients with a history of differentiated thyroid cancer (DTC) (strength of ...
Do intercontraction intervals predict when a woman at term should seek evaluation of labor?
(Family Physicians Inquiries Network, 2009)
A reduction in the intercontraction interval is associated with active labor (strength of recommendation [SOR]: B, cohort study). Most primigravidas who have had regular contractions for 2 hours and multigravidas who have ...
Sums and products in finite fields: an integral geometric viewpoint
(2007)
We prove that if $A \subset {\Bbb F}_q$ is such that $$|A|>q^{{1/2}+\frac{1}{2d}},$$ then $${\Bbb F}_q^{*} \subset dA^2=A^2+...+A^2 d \text{times},$$ where $$A^2=\{a \cdot a': a,a' \in A\},$$ and where ${\Bbb F}_q^{*}$ ...
How accurate is an MRI at diagnosing injured knee ligaments?
(Family Physicians Inquiries Network, 2010)
MRI is highly accurate in diagnosing injury to the anterior cruciate ligament (ACL) (strength of recommendation [SOR]: A, prospective blinded cohort studies) and posterior cruciate ligament (PCL) (SOR: B, limited number ...
Ubiquity of simplices in subsets of vector spaces over finite fields
(2007)
We prove that a sufficiently large subset of the $d$-dimensional vector space over a finite field with $q$ elements, $ {\Bbb F}_q^d$, contains a copy of every $k$-simplex. Fourier analytic methods, Kloosterman sums, and ...
Optical Constants of Silicon Carbide for Astrophysical Applications. II. Extending Optical Functions from Infrared to Ultraviolet Using Single-Crystal Absorption Spectra
(American Astronomical Society, 2009)
Laboratory measurements of unpolarized and polarized absorption spectra of various samples and crystal structures of silicon carbide (SiC) are presented from 1200-35000 cm−1 (λ ∼ 8-0.28 μm) and used to improve the
accuracy ...
When is it OK for children to start drinking fruit juice?
(Family Physicians Inquiries Network, 2009)
Children should be at least 6 months of age (strength of recommendation [SOR]: C, expert opinion) and parents should provide only 100% fruit juice in a cup (not a bottle). Intake should be limited to 4 to 6 oz a day until ...
Should you use antibiotics to treat acute otitis media in children?
(Family Physicians Inquiries Network, 2009)
Antibiotics are not necessary to treat uncomplicated acute otitis media (AOM) in an otherwise healthy child (strength of recommendation [SOR]: A, systematic review). Children younger than 2 years and children with bilateral ...
Angiotensin Blockade in Patients with Diabetic Nephropathy
(Family Physicians Inquiries Network, 2007)
When used to delay the progression of early nephropathy in patients with type 2 diabetes mellitus, angiotensin receptor blockers (ARBs) are not superior to angiotensin-converting enzyme (ACE) inhibitors. (Strength of ...
Glycemic Control in Patients with Type 2 Diabetes
(Family Physicians Inquiries Network, 2007)
There is no clearly superior oral agent for glycemic control in patients with type 2 diabetes. (Strength of Recommendation [SOR]: C) Metformin (Glucophage) has shown additional benefit when compared with other treatments ...
Is combining ACE inhibitors and ARBs helpful or harmful?
(Family Physicians Inquiries Network, 2004)
The combination of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) has been studied for treatment of heart failure, hypertension, and proteinuric renal disease. Combination therapy ...
What predicts a successful smoking cessation attempt?
(Family Physicians Inquiries Network, 2006)
Quit date abstinence (strength of recommendation [SOR]: B, based on low-quality randomized controlled trial [RCT] of healthy subjects) and refraining from tobacco products within the first 2 weeks after an attempt (SOR: ...
What behavioral interventions are safe and effective for treating obesity?
(Family Physicians Inquiries Network, 2006)
Interventions that include a combination of behavioral and lifestyle modification -- including decreased caloric intake, specific aids to changing diet, increased physical activity, and treatment of binge eating disorders ...
What are appropriate screening tests for infants and children?
(Family Physicians Inquiries Network, 2006)
There is adequate evidence for screening neonates for hemoglobinopathies, congenital hypothyroidism, phenylketonuria (strength of recommendation [SOR]: A), and cystic fibrosis (SOR: B). Vision screening should be done for ...
What is the most effective management of acute fractures of the base of the fifth metatarsal?
(Family Physicians Inquiries Network, 2006)
For acute Jones' fractures in recreationally active patients, early intramedullary screw fixation results in lower failure rates and shorter times to both clinical union and return to sports than non-weightbearing short ...