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Now showing items 1401-1420 of 1876
Novel Prodrugs and Self-Assembling Nanocarriers to Improve Drug Delivery
(University of Missouri -- Kansas City, 2018)
PART I: DIPEPTIDE PRODRUG APPROACH TO IMPROVE INTESTINAL
ABSORPTION OF LOPINAVIR
Lopinavir (LPV), a highly potent second-generation HIV-1 protease inhibitor, is
currently indicated in HIV-1 infection. However, poor ...
The influence of type II cytokines in central tolerance
(University of Missouri--Columbia, 2021)
While the genetic elements of many autoimmune conditions have been established, many environmental factors remain a mystery. Exposure to certain infections has been implicated as a possible explanation for the significantly ...
Development of high protein soybean experimental lines with enhanced sulfur amino acid content
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Soybean is one of the most important field crops grown in the United States. Commercial soybeans contain about 36 - 40 [percent] protein and 18 - 20 [percent] oil, by dry weight...
"One foot on the other side" : suicideality in contemporary African diaspora fiction
(University of Missouri--Columbia, 2020)
When this dissertation first began to take shape, it was in response to a period of wide reading of African diaspora fiction--my comprehensive exam preparations-- wherein I began noticing the sheer number of suicides I was encountering. After some...
An interpretable protein localization prediction framework
(University of Missouri--Columbia, 2021)
at https://www.mu-loc.org/....
The nature of evidence utilized in healthcare architectural design decisions at five Midwestern critical access hospitals
(University of Missouri--Columbia, 2020)
Building a replacement hospital is a once in a lifetime experience for any healthcare administrator and the design decisions made during the building process can have a lasting impact on stake holders and end users for ...
Atypical localization of Eph-RTKs in childhood cancer rhabdomyosarcoma
(University of Missouri--Columbia, 2019)
Rhabdomyosarcoma (RMS), the most common soft tissue tumor in children, is an aggressive cancer with a 5-year survival rate of 24% if it has metastasized. Current treatment options are limited to surgery, chemotherapy and ...
Three essays on innovation, corporate control and household consumption-based asset pricing
(University of Missouri--Columbia, 2021)
Chapter I: Tracking more than 100 billion weekly transactions of two million products at the barcode level from 2007 to 2017, we identify and categorize new products as pioneers, followers and improvers to study corporate ...
Development of a portable total-stress measurement instrument
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This research explores the application of ultrasonic stress measurement (USM) technologies to assess stress levels in gusset plates with the development of a small portable tool...
Teacher Reported Preparedness: A Study of One Midwest Metropolitan School District
(2013)
The ultimate purpose of school lies in the success and achievement of its students. Therefore, efforts must be made to continuously improve achievement for every student. What the teacher knows and can do in the classroom ...
Porous silicates for applications in smart water treatment systems and antimicrobial biomedical coatings
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Porous silicates, particularly ordered ones, may find novel and wide-ranging applications in the bioengineering arena in the near future. For instance, zeolites, a family...
Disentangling alcohol-specific alcohol use disorder criteria from externalizing psychopathology using an empirically driven approach
(University of Missouri--Columbia, 2020)
Within current mental disorder classification systems, alcohol use disorder (AUD) and psychopathology, more broadly, are conceptualized as distinct categorical disorders. Recent classification research has focused on ...
Elephant in the room : a study of the impact of emotional experiences on burnout among Chinese reporters
(University of Missouri--Columbia, 2020)
This dissertation is conceived to examine the emotional labor of Chinese frontline reporters and its effects on their job burnout. For both detailed descriptive and generalizable findings, the mixed-method approach combining qualitative in...
Structural studies of flavoprotein inhibitors and inactivators
(University of Missouri--Columbia, 2020)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Flavoenzymes have a versatile capacity to catalyze a wide range of reactions, using their flavin cofactor. In this thesis, work on two flavoenzymes is presented...
Essays on intergenerational transmission in Korea
(University of Missouri--Columbia, 2021)
This dissertation studies the effects of parents' resources on children's labor market outcomes in Korea. The educational structure in Korea has changed substantially with rapid economic growth over the last several decades. There is a substantial...
Experimental and analytical investigation of localization and post-peak behavior of steel members in tension
(University of Missouri--Columbia, 2019)
Accurate simulation of extreme limit states in structures subjected to abnormal loads, earthquake, or blast requires detailed understanding of their post-peak behavior. In steel structures, these extreme-limit states are ...
From unique killers to a jumbo genome - isolation and characterization of phages that infect the plant pathogen, Agrobacterium tumefaciens
(University of Missouri--Columbia, 2019)
Bacteriophages and their lytic peptides can protect plants from phytopathogens such as Agrobacterium tumefaciens. To better understand mechanisms of phagemediated host killing, we isolated and characterized five lytic ...
Molecular characterization of CLE peptide mimicry during cyst nematode pathogenesis
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Plant-parasitic cyst nematodes establish intimate parasitic relationships with their hosts by penetrating the root as motile juveniles and migrating intracellularly until...
Social networks of friendship in the writings of early medieval english women
(University of Missouri--Columbia, 2021)
. The main argument presented in this dissertation contends that early medieval English women formed social networks, in some cases friendships, with other women in order to maintain productive networks of women that yielded preservation of their properties...
The influence of gender on the careers of women theatre faculty in higher education : a qualitative investigation
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Researchers have long documented issues with gender equity in higher education, especially in STEM fields, but less attention has been directed to gender equity in fields...