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Now showing items 141-160 of 295
Bone marrow failure associated with CD8 T-cell expansion in a patient with trichorhinophalangeal syndrome and common variable immunodeficiency [abstract]
(2010-02)
Objective: To report a case of trichorhinophalangeal syndrome coexistent with common variable immunodeficiency (CVID)-like phenotype with a polyclonal expansion of CD8 T-cells Case: A 34-year-old white woman with multiple ...
Angiotensin converting enzyme modulates corneal angiogensis in vivo
(2010-02)
Purpose: We tested (i) whether a renin-angiotensin system exists within the cornea, and (ii) its role in modulating corneal neovascularization (CNV) in vivo. Methods: Rabbit corneal fibroblast and corneal epithelial cell ...
Brain MS imaging after ischemic stroke in mice : insight for brain injury by abnormal proteolysis [abstract]
(2010-02)
Stroke, the 3rd leading cause of death in the US, is caused by blood clotting in the cerebral arteries leading to brain oxygen deprivation and cerebral infarction. To represent the stroke condition, we produced a mouse ...
Chronic ethanol exposure affects adenosinergic mechanism in basal forebrain [abstract]
(2010-02)
Acute ethanol exposure promotes sleep. Chronic ethanol produces insomnia and disrupts sleep. Adenosine promotes sleep by inhibiting wakefulness-promoting neurons in the basal forebrain (BF) via the activation of A1 receptors ...
Bisphosphonate therapy, wound healing and the pathobiology of osteonecrosis of the jawbone [abstract]
(2010-02)
Bisphosphonates (BP) like Zometa (ZA) are widely used to treat complications of bony metastases in cancer patients, with 3 million patients receiving BP therapy worldwide. A serious adverse event occurs in 1-12% of patients ...
Binge ethanol drinking causes protracted insomnia [abstract]
(2010-02)
Binge drinking, loosely defined as rapid and excessive drinking, is a welldocumented behavior especially among teens. However, there are no reports on the effects of binge drinking on sleep. Since sleep is critical for ...
Combined augmentation mastoplexy [abstract]
(2010-02)
Background: First described by Gonzales-Ullo in 1960, combined augmentation/mastopexy has increased in popularity amongst patients interested in a single stage procedure that reduces cost and decreases recovery time. The ...
Intrathecal baclofen as a pharmacologic treatment for tactile defensiveness and symptoms of autism spectrum disorder [abstract]
(2010-03)
Patient: An 18-year-old male with Autism Spectrum Disorder (ASD) and Tactile Defensiveness suffered a traumatic brain injury (TBI). Case Description: Pre-TBI, the patient exhibited mild tactile defensiveness but was ...
Interpreting the origins of the human hip : Evaluation of articular contact area in the ancestral hip joint [abstract]
(2010-03)
Understanding hip joint functional anatomy is critical to interpreting the origins of the human hip. A new pelvis of the 9 million year old ape Rudapithecus, argued to represent a close African ape-human relative, provides ...
Infection and massive bone marrow necrosis in the treatment of thrombotic thrombocytopenia purpura (TTP) [abstract]
(2010-03)
Bone marrow necrosis (BMN) is a rare entity and until recently has been a postmortem phenomenon. Most ante-mortem cases are associated with underlying malignancy, primarily leukemias and lymphomas. Rarely, it is the result ...
How are the yeast cyclins, PCL6 and PCL7 regulated in the GLC7 pathway? [abstract]
(2010-03)
The eukaryotic Protein Phosphatase 1 (PP1) is a serine/threonine phosphatase that is encoded by the essential gene, GLC7, in Saccharomyces cerevisiae (budding yeast). The Glc7 protein is involved in the regulation of ...
In vivo and in vitro evaluation of MRI contrast agent targeting human prostate cancer [abstract]
(2010-03)
Prostate cancer is the most common cancer for men in the US, affecting 1 in 6 men. Noninvasive imaging techniques have played important roles in prostate cancer staging and treatment planning. In particular, diffusion-weighted ...
In vivo and in vitro evaluation of 64 CU-labeled bombesin analogs for targeting gastrin-releasing peptide receptors on human prostate cancer [abstract]
(2010-03)
Introduction: Gastrin-releasing peptide receptors (GRPr) are expressed in high numbers on human prostate cancer. The bombesin peptide derivative, BBN(7- 14)NH2, has high affinity and selectivity to GRPr. Therefore, Copper-64 ...
Local ethanol promotes extracellular accumulation of adenosine in the orexinergic perifornical hypothalamus [abstract]
(2010-03)
Ethanol promotes sleep. However, the neuroanatomical site where ethanol acts to modulate sleep/wakefulness is unknown. The perifornical hypothalamus (PFH) contains wake-promoting orexinergic neurons. Studies from our ...
Gaining understanding of South African traditional helers' management of lymphedema following breast cancer treatment : building a foundation for a synergistic model of best practices [abstract]
(2010-03)
As of 1999, breast cancer (BC) was the leading cause of cancer diagnosis in South African women, affecting 1 in 12 Caucasian and 1 in 18 ethnically diverse South African women. In order to improve BC survivorship, the ...
Comparison of different strategies in parathyroid scintigraphy imaging [abstract]
(2010)
To retrospectively compare the various scintigraphic methods to discover the most accurate protocol for preoperative localization of single-gland disease, medical records of 710 patients, diagnosed with primary were reviewed. ...
Development of biospecimen sample preparation techniques for molecular imaging using ultra-high resolution mass spectrometry [abstract]
(2010)
Matrix assisted laser desorption ionization (MALDI) imaging is a technique which analyzes and maps the distribution of molecules in two-dimensional biospecimens, such as histological tissue sections. To-date, the classifications ...
Immediate versus delayed percutaneous coronary intervention for patients with non-ST elevation-acute coronary syndrome : a meta-analysis of randomised trials [abstract]
(2010)
Studies have indicated that an early invasive strategy is favorable over a selective invasive strategy for Non-ST segment elevation acute coronary syndromes (NSTE-ACS). However, there is no general consensus on precisely ...
Integrin-linked kinase : a potential player in ovarian cancer metastesis [abstract]
(2010)
Epithelial ovarian cancer (EOC) is the fifth leading cause of overall cancer death among American women. In 2008, 15,520 deaths were directly attributed to EOC, and an additional 21,650 cases were diagnosed. When EOC is ...
Effects of statins on metabolic adaptations to aerobic exercise training : preliminary findings [abstract]
(2010)
Emerging evidence suggests statins, unlike exercise, may cause deleterious effects on skeletal muscle oxidative capacity and insulin sensitivity. The purpose of this study was to determine if daily statin therapy altered ...