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Now showing items 161-180 of 191
Imaging 3D tissue fiber organization using optical polarization tractography
(University of Missouri--Columbia, 2017)
Optical polarization tractography (OPT) is a new imaging technology developed based on an advanced Jones matrix implementation of polarization-sensitive optical coherence tomography (PSOCT). OPT can acquire high-resolution, ...
Development of a composite acellular tissue graft for musculoskeletal tissue engineering
(University of Missouri--Columbia, 2015)
A composite acellular tissue graft comprised of decellularized tendon conjugated with nanomaterials has been developed for musculoskeletal tissue engineering applications. The focus of this dissertation is on the development ...
Rapid detection and characterization of mycobacteria using microchannel electrical impedance spectroscopy
(University of Missouri--Columbia, 2017)
The presence of virulent, pathogenic bacteria in our body, food, water and other consumables is harmful and causes enormous economic and personal losses. Here we will be looking at developing a platform technology that can ...
Development of a multispectral sensor for crop canopy temperature measurement
(University of Missouri--Columbia, 2017)
The Multispectral System for Imaging of a Crop Canopy (MSICC) that combines a miniature long wavelength infrared (LWIR) camera with a visible camera was developed to capture a field of view and derive a plant specific ...
Structure/function studies of CFTR's pore-forming domain reveal evolutionary divergence between CFTR and ABC transporters
(University of Missouri--Columbia, 2015)
Cystic Fibrosis Transmembrane conductance Regulator (CFTR) is the culprit behind Cystic Fibrosis (CF), a genetic disease highly occurs among Caucasians. Studying the structure/function of CFTR chloride channel not only ...
Peptide nanoconjugates for tissue diagnostics and molecular imaging
(University of Missouri--Columbia, 2016)
The rise of targeted therapy in cancer treatment has created a strong need for characterization of a patient's tumor before receiving treatment. Many effective cancer drugs are now being targeted to specific proteins present ...
I. Infection control: exploration of siliceous zeolite MFI films as coatings for implantable devices II. Alternative approaches for post-operative infection control using pre-and pro-biotics: a meta-analysis
(University of Missouri--Columbia, 2022)
The prevention and control of infections associated with indwelling medical implants has remained a top goal for biomedical researchers and clinicians in associated fields. Multiple routes have been explored for this ...
Nanofibrillation of lignocellulosic biomass into lignin-containing nanocellulose for 3D printing and antimicrobial applications
(University of Missouri--Columbia, 2022)
Lignin-containing nanocellulose (LNC) has become an emerging subcategory of nanocellulose. Compared toedtraditional pure nanocellulose, LNC contains lignin and hemicellulose that are not fully removed from original ...
Risk prediction and an injectable collagen material for intervertebral disc degeneration
(University of Missouri--Columbia, 2021)
This research primarily focuses on early prediction and treatment for intervertebral disc degeneration (IVDD). In Phase 1, machine learning algorithms were evaluated to predict the risk of intervertebral disc degeneration ...
Methods for improved kinematic measurements of the lower extremities
(University of Missouri--Columbia, 2022)
An understanding of knee dynamics is vital to treat neurological and musculoskeletal conditions that affect the lower extremities and achieve peak performance from athletes. To obtain and analyze kinematics and kinetics ...
Imaging structurual and mechanical properties in cardiovascular tissue using optical polarization tractography
(University of Missouri--Columbia, 2022)
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the US. Every 36 seconds, one person dies from CVD [1]. Structural deficiencies and secondary changes induced by either abnormal functioning ...
Degradation of the veterinary antibiotics in swine manure via anaerobic digestion
(University of Missouri--Columbia, 2021)
Antimicrobial resistance is becoming an imminent danger for human health, in part because of excessive consumption of antibiotics in the animal industry. Laboratory-scale anaerobic digesters (ADs) were utilized to investigate ...
The design of fluorescence correlation spectroscopy for single molecule techniques
(University of Missouri--Columbia, 2019)
The ribosome is responsible for protein synthesis--a critical process in creating essential proteins for cell survival. Though bulk techniques yield valuable results about the structure of the ribosome, bulk techniques are ...
Lignin dissolution in deep eutectic solvents : a molecular dynamics study
(University of Missouri--Columbia, 2020)
Deep eutectic solvents (DESs) have shown great potential on lignocellulosic biomass pretreatment. Many DESs are capable of extracting lignin from biomass and dissolving hemicellulose while preserving most of cellulose in ...
Direct from sample phenotypic antibiotic susceptibility testing
(University of Missouri--Columbia, 2018)
To transition from broad-spectrum antibiotic therapy to a more effective "targeted" therapy, i.e. in order to determine whether the infecting strain is resistant or susceptible to individual candidate antibiotics, clinicians ...
The impact of adverse maternal environments on resistance artery function and mechanical characteristics in offspring
(University of Missouri--Columbia, 2020)
Cardiovascular disease is one of the leading causes of death worldwide. Maternal obesity, gestational diabetes mellitus (GMD) and assisted reproductive technologies (ART) have been associated with cardiovascular deficiencies ...
Development of UAV-based high-throughput phenotyping technologies towards improving soybean breeding efficiency
(University of Missouri--Columbia, 2021)
Development of new crop varieties with improved traits through crop breeding programs is one of the promising solutions for the estimated food crisis in 2050 when agricultural production needs to double its current growth ...
Detecting estrus in sows using a robotic imaging system and neural networks
(University of Missouri--Columbia, 2023)
The global demand for pork products is expected to grow further with the growth of the population. Traditional swine farming presents disadvantages such as low breeding efficiency and high labor cost. Estrus detection is ...
Automated detection of amperometric spikes resulting from quantal exocytosis and estimation of spike and pre-spike foot signal parameters
(University of Missouri--Columbia, 2018)
Electrochemical microelectrodes can detect single-vesicle release events as "spikes" of amperometric current. We developed a template based "matched-filter" approach that performs least squares fit of a library of templates ...
Quantifying the effect of environments on crop emergence, development and yield using sensing and deep learning techniques
(University of Missouri--Columbia, 2021)
The world population is estimated to increase by 2 billion in the next 30 years, and global crop production needs to double by 2050 to meet the projected demands from rising population, diet shifts, and increasing biofuels ...