Stadler Genetics Symposia, volume 08, 1976 (MU)https://hdl.handle.net/10355/665192024-03-28T16:48:17Z2024-03-28T16:48:17ZAphrodisiacs and anaphrodisiacs : better loving through chemistry : reproduction, behavior, pheromones, love potions, biological controlCarrel, James E.https://hdl.handle.net/10355/665792019-03-12T09:01:47Z1976-01-01T00:00:00ZAphrodisiacs and anaphrodisiacs : better loving through chemistry : reproduction, behavior, pheromones, love potions, biological control
Carrel, James E.
Reproductive behavior in animals is modulated by an assortment of chemical signals. This paper focuses on substances that are externally emitted and are effective when a male and female are near or in contact with each other. Aphrodisiacs enhance an individual's propensity to mate, whereas anaphrodisiacs have the opposite affect. Both classes of chemicals occur intrinsically in insects and vertebrates. The existence either of intrinsic or of extrinsic aphrodisiacs and anaphrodisiacs in humans is suspected. Sexual modulators help us understand basic processes in animal reproduction. Further more, they may become important biological control agents. Genetics offers a valuable, but very under-exploited, approachin studies of intraspecific chemical communication.
1976-01-01T00:00:00ZThe development of new drugs for genetic diseasesCerami, Anthonyhttps://hdl.handle.net/10355/665802019-03-12T09:01:49Z1976-01-01T00:00:00ZThe development of new drugs for genetic diseases
Cerami, Anthony
The genetic diseases of man constitute a unique challenge to the medical scientist. For the past several years our laboratory has been developing new drugs for two of the more common genetic diseases - sickle cell anemia and thalassemia. The status of the development of sodium cyanate as the first chemometallactic agent for the treatment of sickle cell anemia and the development of new iron chelating agents for the treatment of iron overload in patients with thalassemia are discussed.
1976-01-01T00:00:00ZDinoflagellate genetics and DNA characterization : (dinoflagellates, evolution, nucleus, DNA, genetics, mesocaryota)Loeblich, Alfred R., IIIhttps://hdl.handle.net/10355/665832019-03-12T09:01:55Z1976-01-01T00:00:00ZDinoflagellate genetics and DNA characterization : (dinoflagellates, evolution, nucleus, DNA, genetics, mesocaryota)
Loeblich, Alfred R., III
Nuclear features of dinoflagellates that were used origin ally to support the Mesocaryota concept are reviewed. Although dinoflagellates possess some procaryotic nuclear features, the remainder of the cell is obviously eucaryotic. The fibrillary diameter of the chromatin, low level of chromosomal basic proteins, membrane attachment of the chromosomes and swirl pattern seen in sectioned chromosomes all support a procaryotic affinity. On the other hand, the repeated and highly complex DNA, S-phase of DNA synthesis, and the presence of basic proteins and extra nuclear spindle support the contention that dinoflagellates are eucaryotic. The possession of both procaryotic and eukaryotic nuclear features indicate that this group evolved relatively early in biological time. A review is made of recent attempts to analyze the genetics of this algal group. Although incomplete, these studies have suggested that dinoflagellates have an unusual meiotic process.
1976-01-01T00:00:00ZDNA packaging in isolated bacterial nucleoids : (chromosomes, DNA tertiary structure, nucleoids, DNA folding, DNA supercoiling, nascent RNA, membrane-DNA)Pettijohn, David E.https://hdl.handle.net/10355/665842019-03-12T09:01:56Z1976-01-01T00:00:00ZDNA packaging in isolated bacterial nucleoids : (chromosomes, DNA tertiary structure, nucleoids, DNA folding, DNA supercoiling, nascent RNA, membrane-DNA)
Pettijohn, David E.
Properties of nucleoids isolated from Escherichia coli are described. Experiments which investigate the organization of DNA folding and supercoiling in the isolated chromosome are reviewed, and evidence is discussed suggesting a role for certain proteins and nascent RNA molecules in stabilizing the condensed DNA. A model of the conformational organization of the packaged DNA is presented.
1976-01-01T00:00:00Z