2017 Health Sciences Research Day (MU)
https://hdl.handle.net/10355/62133
2024-03-29T07:26:07ZAngiotensin II deregulates mitochondrial quality control and prevents autophagosome formation in skeletal muscle
https://hdl.handle.net/10355/62146
Angiotensin II deregulates mitochondrial quality control and prevents autophagosome formation in skeletal muscle
Silva, Kleiton A. S.; Delafontaine, Patrice; Yoshida, Tadashi
Conclusion: Ang II suppresses autophagy by impairing autophagosome formation, which leads to accumulation of damaged mitochondria and ubiquitinated proteins. Our data strongly suggest that autophagy plays a critical role in Ang II-induced energy imbalance and skeletal muscle wasting, and that it could be a new therapeutic target in wasting disorders such as HF.
Poster presented at the 2017 Health Sciences Research Day which was organized and sponsored by the University of Missouri School of Medicine Research Council and held on November 9, 2017.
2017-01-01T00:00:00ZAnkle fracture complications in the elderly
https://hdl.handle.net/10355/62262
Ankle fracture complications in the elderly
Polk, Andrew J.; Buck, Brian W.; Robertson, Michael W.; Cook, James L.; Felton, Courtney L.
Objectives: To determine whether the rate of complications is higher in geriatric patients who undergo operative fixation at our institution for unstable ankle fractures or fracture dislocations ; To determine if geriatric patients require a prolonged time for the ankle fracture personality to declare itself amenable to definitive fixation. Conclusions: Complication rates following operative fixation of fractures and fracture dislocations at our institution are not significantly increased in the geriatric patient population relative to the non-geriatric population ; The geriatric patient population does not require a prolonged period of time for the fracture personality to declare itself amenable to definitive surgical fixation.
Poster presented at the 2017 Health Sciences Research Day which was organized and sponsored by the University of Missouri School of Medicine Research Council and held on November 9, 2017.
2017-01-01T00:00:00ZCharacterization of the dorsal ulnar corner in distal radius fractures : implication for surgical decision making
https://hdl.handle.net/10355/62159
Characterization of the dorsal ulnar corner in distal radius fractures : implication for surgical decision making
Zimmer, Joe; Bridgeman, Jay T.; Pfeiffer, Ferris M.; Brogan, David M.
Conclusions: 3D segmentation software is effective in producing 3D distal radius fracture models that can be used for analysis. The study demonstrated a pattern in dorsal ulnar corner fragment shape, though the study population size should be increased to improve the power of the results. The data will improve understanding of the morphology and size of the dorsal ulnar corner fracture fragment, which is critical to understanding the optimal method of operative fixation. This information will also lead to development of more accurate intra-articularfracture models for biomechanical studies.
Poster presented at the 2017 Health Sciences Research Day which was organized and sponsored by the University of Missouri School of Medicine Research Council and held on November 9, 2017.
2017-01-01T00:00:00ZCreation of a database, inconsistencies that arise, and implications on clinical outcomes for patients undergoing MRI fusion prostate biopsy
https://hdl.handle.net/10355/62148
Creation of a database, inconsistencies that arise, and implications on clinical outcomes for patients undergoing MRI fusion prostate biopsy
Lee, Hillary; Wakefield, Mark; Murray, Katie S.
Conclusion: Accurate clinical charting and information is highly critical for quality patient care and follow up ; The utilization of MRI fusion biopsy identified prostate cancer in 60.7% of screened patients compared to historical 25% using standard biopsy ; Our results show the potential need for a charting template that captures all relevant information, otherwise there is variable and incomplete data collection. This demonstrates the potential need for a phase 2 of this project.
Poster presented at the 2017 Health Sciences Research Day which was organized and sponsored by the University of Missouri School of Medicine Research Council and held on November 9, 2017.
2017-01-01T00:00:00Z