Browsing University of Missouri-Columbia by Thesis Advisor "Tanner, John J."
Now showing items 1-5 of 5
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Structural and kinetic studies of human aldh7a1 and aldh9a1
(University of Missouri--Columbia, 2021)The regulation and detoxification of endogenously and exogenously derived aldehydes is paramount to cellular survival due to the highly reactive nature of aldehydes as electrophiles. Human aldehyde dehydrogenases (ALDHs) ... -
Structural and kinetic studies of proline metabolic enzyme inhibitors and inactivators
(University of Missouri--Columbia, 2021)Structural and kinetic studies of the proline metabolic enzymes proline dehydrogenase (PRODH), [delta]1-pyrroline-5-carboxylate reductase (PYCR), and aldehyde dehydrogenase 4A1 (ALDH4A1) are presented in this thesis. ... -
Structural studies of domain of unknown function 507 (DUF507)
(University of Missouri--Columbia, 2023)The crystal structure of the domain of unknown function family 507 protein from Aquifex aeolicus is reported (AaDUF507, UniProt O67633, 183 residues). The structure was determined in two space groups (C2221 and P3221) at ... -
Structural studies of type B proline utilization A (PutA) proteins
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This thesis addresses the structural studies of the type B proline utilization A (PutA) proteins. Proline utilization A (PutA) catalyzes the oxidation ... -
Structure of an antigen-binding fragment bound to stem-loop DNA and crystallization of recombinant haemophilus influenzae e(P4) acid phosphatase
(University of Missouri--Columbia, 2006)DNA-1 and 11F8 are anti-ss DNA antibodies derived from autoimmune lupus-prone mice. They are very similar to each other in terms of CDR sequence and preference for binding T-rich ss DNA. G1-17 is an oligonucleotide identified ...