Is oral prednisone as effective as high-dose IV steroids as initial treatment in a patient with a COPD exacerbation?
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For the initial inpatient management of chronic obstructive pulmonary disease (COPD) exacerbations in noncritically ill patients, oral steroids are associated with similar outcomes as intravenous (IV) steroids. In addition, patients treated initially with oral steroids appear to have shorter hospital stays and lower hospital costs. (SOR: B, based on an RCT and a cohort study.)
Evidence Based Practice 14(2): 08.