Exposure Assessment for Endocrine Disruptors: Some Considerations in the Design of Studies

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Exposure Assessment for Endocrine Disruptors: Some Considerations in the Design of Studies

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/10167

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dc.contributor.author Rice, Carol Helen
dc.contributor.author Birnbaum, Linda S.
dc.contributor.author Cogliano, Vincent James
dc.contributor.author Mahaffey, Kathryn R., 1943-
dc.contributor.author Needham, Larry L.
dc.contributor.author Rogan, Walter J.
dc.contributor.author vom Saal, Frederick S.
dc.date.accessioned 2011-03-09T15:31:30Z
dc.date.available 2011-03-09T15:31:30Z
dc.date.issued 2003-10
dc.identifier.citation Rice C, Birnbaum LS, Cogliano J, Mahaffey K, Needham L, et al. 2003 Exposure Assessment for Endocrine Disruptors: Some Considerations in the Design of Studies. Environmental Health Perspectives 111(13): 1683-1690. en_US
dc.identifier.uri http://hdl.handle.net/10355/10167
dc.description Reproduced with permission from Environmental Health Perspectives. doi:10.1289/ehp.5798 en_US
dc.description.abstract In studies designed to evaluate exposure-response relationships in children's development from conception through puberty, multiple factors that affect the generation of meaningful exposure metrics must be considered. These factors include multiple routes of exposure; the timing, frequency, and duration of exposure; need for qualitative and quantitative data; sample collection and storage protocols; and the selection and documentation of analytic methods. The methods for exposure data collection and analysis must be sufficiently robust to accommodate the a priori hypotheses to be tested, as well as hypotheses generated from the data. A number of issues that must be considered in study design are summarized here. en_US
dc.language.iso en_US en_US
dc.publisher National Institute of Environmental Health Sciences en_US
dc.relation.ispartof Biological Sciences publications (MU)
dc.subject chemical exposure en_US
dc.subject.lcsh Endocrine disrupting chemicals en_US
dc.subject.lcsh Child development en_US
dc.subject.lcsh Epidemiology en_US
dc.title Exposure Assessment for Endocrine Disruptors: Some Considerations in the Design of Studies en_US
dc.type Article en_US
dc.source.harvested Environmental Health Perspectives Web site. en_US
dc.relation.ispartofcommunity University of Missouri-Columbia. College of Arts and Sciences. Division of Biological Sciences


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