Is a D-dimer test useful in predicting future clot development after completion of vitamin K antagonist therapy for an unprovoked PE or DVT?
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The use of a D-dimer assay 1 month after the conclusion of vitamin K antagonist (VKA) therapy for an unprovoked pulmonary embolism (PE) or deep vein thrombosis (DVT) is helpful in identifying individuals who may be at higher risk of having another venous thromboembolism (VTE). (SOR: A, based on multiple systematic reviews.) Clinically, however, the decision to continue or stop VKA therapy should also take in to account the presence or absence of other sources of thromboembolic risk. (SOR: C, based on expert opinion.)
Evidence Based Practice 14(3): 11.