dc.contributor.advisor | Grant, Sheila Ann | eng |
dc.contributor.advisor | Gangopadhyay, Shubhra | eng |
dc.contributor.author | Stringer, R. Cody, 1983- | eng |
dc.date.issued | 2010 | eng |
dc.date.submitted | 2010 Fall | eng |
dc.description | Title from PDF of title page (University of Missouri--Columbia, viewed on December 7, 2010). | eng |
dc.description | The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. | eng |
dc.description | Dissertation advisor: Dr. Sheila A. Grant and Dr. Shubhra Gangopadhyay. | eng |
dc.description | Vita. | eng |
dc.description | Ph. D. University of Missouri--Columbia 2010. | eng |
dc.description.abstract | A sensing device for explosive compounds is a fundamental step towards the capability to detect the presence of landmines, improvised explosive devices (IEDs), and other unexploded ordinance. To detect high explosive compounds such as 2,4,6-trinitrotoluene (TNT), an optical sensor utilizing molecularly imprinted polymer (MIP) technology was developed. This sensor consists of MIP microparticles prepared using methacrylic acid as the functional monomer in a precipitation polymerization reaction. The MIP particles are combined with fluorescent semiconductor nanocrystals, or quantum dots, via a simple crosslinking procedure. The MIP is then capable of rebinding the explosive compound, which quenches the fluorescence of the covalently linked quantum dots. After preliminary studies of the basic sensing mechanism, a precipitation polymerization reaction was used to create MIP particles with a uniform spherical shape and sub-micron size, as well as MIP particles with a porous mesh-like morphology. A comparison study of these two types of particles indicated that the MIP microspheres were more effective at binding the nitroaromatic explosive TNT and its breakdown product 2,4-dinitrotoluene (DNT). The MIP microsphere-based fluorescence sensing scheme was then entrapped into a sol-gel matrix and applied to a solid substrate sensor platform for detection of vapor-phase explosives. However, the detection method showed poor performance and was unsuitable for sensing of airborne nitroaromatic explosive compounds. | eng |
dc.description.bibref | Includes bibliographical references. | eng |
dc.format.extent | vi, 89 pages | eng |
dc.identifier.oclc | 707644635 | eng |
dc.identifier.uri | https://hdl.handle.net/10355/10244 | |
dc.identifier.uri | https://doi.org/10.32469/10355/10244 | eng |
dc.language | English | eng |
dc.publisher | University of Missouri--Columbia | eng |
dc.relation.ispartofcommunity | University of Missouri--Columbia. Graduate School. Theses and Dissertations | eng |
dc.rights | OpenAccess. | eng |
dc.rights.license | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. | |
dc.source | Submitted by University of Missouri--Columbia Graduate School. | eng |
dc.subject.lcsh | Explosives -- Detection | eng |
dc.subject.lcsh | Nitroaromatic compounds -- Environmental aspects | eng |
dc.subject.lcsh | Explosives -- Environmental aspects | eng |
dc.subject.lcsh | TNT (Chemical) -- Environmental aspects | eng |
dc.title | Molecularly imprinted polymer labeled with quantum dots for detection of nitroaromatic explosives | eng |
dc.type | Thesis | eng |
thesis.degree.discipline | Biological engineering (MU) | eng |
thesis.degree.grantor | University of Missouri--Columbia | eng |
thesis.degree.level | Doctoral | eng |
thesis.degree.name | Ph. D. | eng |