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dc.contributor.advisorGrant, Sheila Anneng
dc.contributor.advisorGangopadhyay, Shubhraeng
dc.contributor.authorStringer, R. Cody, 1983-eng
dc.date.issued2010eng
dc.date.submitted2010 Falleng
dc.descriptionTitle from PDF of title page (University of Missouri--Columbia, viewed on December 7, 2010).eng
dc.descriptionThe entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file.eng
dc.descriptionDissertation advisor: Dr. Sheila A. Grant and Dr. Shubhra Gangopadhyay.eng
dc.descriptionVita.eng
dc.descriptionPh. D. University of Missouri--Columbia 2010.eng
dc.description.abstractA sensing device for explosive compounds is a fundamental step towards the capability to detect the presence of landmines, improvised explosive devices (IEDs), and other unexploded ordinance. To detect high explosive compounds such as 2,4,6-trinitrotoluene (TNT), an optical sensor utilizing molecularly imprinted polymer (MIP) technology was developed. This sensor consists of MIP microparticles prepared using methacrylic acid as the functional monomer in a precipitation polymerization reaction. The MIP particles are combined with fluorescent semiconductor nanocrystals, or quantum dots, via a simple crosslinking procedure. The MIP is then capable of rebinding the explosive compound, which quenches the fluorescence of the covalently linked quantum dots. After preliminary studies of the basic sensing mechanism, a precipitation polymerization reaction was used to create MIP particles with a uniform spherical shape and sub-micron size, as well as MIP particles with a porous mesh-like morphology. A comparison study of these two types of particles indicated that the MIP microspheres were more effective at binding the nitroaromatic explosive TNT and its breakdown product 2,4-dinitrotoluene (DNT). The MIP microsphere-based fluorescence sensing scheme was then entrapped into a sol-gel matrix and applied to a solid substrate sensor platform for detection of vapor-phase explosives. However, the detection method showed poor performance and was unsuitable for sensing of airborne nitroaromatic explosive compounds.eng
dc.description.bibrefIncludes bibliographical references.eng
dc.format.extentvi, 89 pageseng
dc.identifier.oclc707644635eng
dc.identifier.urihttps://hdl.handle.net/10355/10244
dc.identifier.urihttps://doi.org/10.32469/10355/10244eng
dc.languageEnglisheng
dc.publisherUniversity of Missouri--Columbiaeng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. Graduate School. Theses and Dissertationseng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
dc.sourceSubmitted by University of Missouri--Columbia Graduate School.eng
dc.subject.lcshExplosives -- Detectioneng
dc.subject.lcshNitroaromatic compounds -- Environmental aspectseng
dc.subject.lcshExplosives -- Environmental aspectseng
dc.subject.lcshTNT (Chemical) -- Environmental aspectseng
dc.titleMolecularly imprinted polymer labeled with quantum dots for detection of nitroaromatic explosiveseng
dc.typeThesiseng
thesis.degree.disciplineBiological engineering (MU)eng
thesis.degree.grantorUniversity of Missouri--Columbiaeng
thesis.degree.levelDoctoraleng
thesis.degree.namePh. D.eng


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