What is the best way to manage postmenopausal patients with osteopenia?
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Alendronate and raloxifene both reduce vertebral fracture rates in postmenopausal women with osteopenia. Risedronate does not alter vertebral fracture rates but does reduce the overall fracture rate for these women. (SOR: C, derived from retrospective and subgroup analyses of cohort studies). Exercise appears to significantly increase bone mineral density (BMD) and T-scores in postmenopausal women. (SOR: C, based on a cohort study using disease-oriented outcomes.)
Evidence Based Practice 14(4): 08-09.