Is capsaicin effective for neuropathic pain?
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With repeated application of a low-dose cream or a single application of a high-dose patch, capsaicin is an effective treatment options for neuropathic pain. (SOR: B, based on a meta-analysis and RCTs.) Estimates of benefit and harm are not robust due to limited amounts of data for different neuropathic conditions and inconsistent outcome definitions.
Evidence Based Practice 14(4): 14.