Browsing 2011 UMKC Dissertations - Freely Available Online by Thesis Department "Cell Biology and Biophysics (UMKC)"
Now showing items 1-3 of 3
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3-Hydroxy-3-methylglutaryl-coenzyme A lyase: investigation of cysteines mediating intersubunit disulfide formation and regulation by thiol/disulfide exchange and discovery of an extramitochondrial homolog
(University of Missouri -- Kansas City, 2012-01-18)3-Hydroxy-3-methylglutaryl-Coenzyme A lyase catalyzes the cleavage of 3-hydroxy- 3-methylglutaryl-Coenzyme A into acetoacetate and acetyl-Coenzyme A, a key reaction in ketogenesis and leucine catabolism. Previous work ... -
Mutational and functional analyses of the dynein heavy chain indicate the existence of an apical-sistal transport cycle in cells
(University of Missouri--Kansas City, 2012-03-02)The organization, survival, and function of eukaryotic cells depend on intracellular transport governed by the microtubule based molecular motors cytoplasmic dynein and kinesin. Dynein carries out the inward transport ... -
Structural and functional studies of type three secretion virulence factors from gram-negative pathogenic bacteria
(University of Missouri-Kansas City, 2011-12-21)Many pathogenic Gram-negative bacteria utilize type III secretion systems (TTSS) to alter the normal functions of target host epithelial cells. Of the 1.1 million deaths that are caused by Shigella each year, nearly a third ...