Therapies for nonalcoholic steatohepatitis (NASH)
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Pharmacologic therapies such as metformin, pioglitazone, vitamin E, and long-chain fatty acids all reduce serum alanine aminotransferase (ALT) levels in patients with NASH; however, effects on liver histology have been inconsistent. (SOR: C, based on systematic reviews that did not assess patient-oriented outcomes.)
Evidence Based Practice 14(5): 01-02.