In evaluating hyponatremia in a patient who is taking a diuretic, is there any value to checking uric acid level?
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Measuring uric acid (either as a simple serum level or as a fractional excretion) may be beneficial in evaluating hyponatremia in patients taking diuretics because it helps differentiate between the syndrome of inappropriate antidiuresis (SIAD) and extracellular volume depletion. (SOR: B, based on diagnostic cohort studies.)
Evidence Based Practice 14(7): 09.