How do the rapid strep antigen tests and throat culture compare when testing for strep?
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Rapid strep tests have higher specificity than sensitivity. (SOR: B, based on cohort studies.) A negative rapid antigen diagnostic test (RADT) should be backed up by a throat culture in children. A RADT can be used as a stand-alone test in adults, or if previously validated as having comparable sensitivity and specificity with a throat culture. (SOR: C, based on expert guidelines.)
Evidence Based Practice 14(8): 10.