What are the risks of recurrent seizures in adults if seizure medications are stopped after a prolonged seizure-free period?

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What are the risks of recurrent seizures in adults if seizure medications are stopped after a prolonged seizure-free period?

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/11619

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Title: What are the risks of recurrent seizures in adults if seizure medications are stopped after a prolonged seizure-free period?
Author: Kriksey, Kiley; Over, Darrell R.
Keywords: seizure relapse
withdrawal group
Date: 2011-09
Publisher: Family Physicians Inquiries Network
Citation: Evidence Based Practice 14(9): 09-10.
Series/Report no.: Help Desk Answers
Abstract: The risk for seizure relapse is increased after discontinuation of antiepileptic drugs (AEDs), with rates ranging from 50% to 57% after 3 to 4 years. (SOR: B, extrapolated from cohort studies.) Patients with normal neurological examination results have a lower rate of recurrence than patients with abnormal results. Patient age, sex, age at seizure onset, duration of seizure, or partial versus generalized seizure are not related to relapse risk. (SOR: B, based on a single RCT with 1-year follow-up.)
URI: http://hdl.handle.net/10355/11619

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